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Porphyromonas gingivalis Search Results

Record: 1 of 1  
MiniMap tRNA-Asn-2 tRNA-Asn-1 IGR0002 IGR0001 IGR0005 IGR0007 IGR0003 IGR0004 IGR0008 IGR1676 IGR0006 ISPg5, - PG0008 ISPg5, - PG0007 PG0003 PG0005 PG0006 PG0002 PG0004 dnaA, - PG0001 clpC, - PG0009 ISPg5, - PG0008 ISPg5, - PG0007 PG0003 PG0005 PG0006 PG0002 PG0004 dnaA, - PG0001 clpC, - PG0009 Type: IS element, Name: ISPg5 - 8 ISPg5, - PG0008 ISPg5, - PG0007 PG0003 PG0005 PG0006 PG0002 PG0004 dnaA, - PG0001 clpC, - PG0009


LANL Gene ID: PG0005

GenBank Locus Tag: PG0005

DNA Molecule Name:
1  

GenBank ID:
34539885

Gene Name:


Definition:
integral membrane protein; phosphoesterase/phosphohydrolase

Cellular Location:
Inner membrane, Cytoplasm [Evidence]

Gene Start:
5041

Gene Stop:
3890

Gene Length:
1152

Molecular Weight*:
43763

pI*:
10.10

Net Charge*:
10.05

EC:
 

Functional Class:
Uncategorized  

Gene Ontology:
Molecular function
  GO:0016787    hydrolase activity


Pathway: pathway table

Comment:
TIGR ID: PG0005

Proteomic Data: Proteomic Data Search
TIGR Annotationconserved hypothetical protein, GroupJ (hypothetical proteins-Conserved)
ORF #PG-PP/PG-PPC1PG-PP/PG-PPC2
Spectral CountPeptide IntensitySpectral CountPeptide Intensity
ProqValProqValProqValProqVal
TIGRPG0005-1.840.0038-1.310.0021-2.017.1e-05-1.310.0021
LANLPG00050.280.400.250.47
ConsensusSP1IP1SP2IP2

Human Oral Microbiome Database:
View in HOMD Genome Viewer

 Blast Summary:  PSI-Blast Search
Several hits in gapped BLAST to integral membrane proteins, some of which are identified as phosphoesterases. (EC 3.1.-.-). Residues 73-374 are 28% similar to a hypothetical protein of Helicobacter (AE001473).

 Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|34539885|ref|NP_904364.1|  hypothetical protein PG0005 [P...   769   0.0  
 gi|154491877|ref|ZP_02031503.1|  hypothetical protein PARMER...   305   4e-81
 gi|150010232|ref|YP_001304975.1|  putative phosphoesterase [...   293   2e-77
 gi|154491876|ref|ZP_02031502.1|  hypothetical protein PARMER...   181   6e-44
 gi|29349547|ref|NP_813050.1|  conserved hypothetical protein...   180   1e-43
 gi|150010233|ref|YP_001304976.1|  conserved hypothetical pro...   180   2e-43
 gi|118727869|ref|ZP_01576454.1|  metallophosphoesterase [Clo...   179   2e-43
 gi|156108850|gb|EDO10595.1|  hypothetical protein BACOVA_040...   177   8e-43
 gi|30019266|ref|NP_830897.1|  phosphoesterase [Bacillus cere...   167   8e-40
 gi|42780287|ref|NP_977534.1|  Ser/Thr protein phosphatase fa...   167   1e-39


InterPro Summary:  InterProScan

InterPro
IPR004843
Domain
Metallophosphoesterase
PF00149 [157-321]T 1.2999992446818E-10 PF00149 Metallophos Metallophos
InterPro
IPR011156
Family
Membrane-bound phosphoesterase HP1044
PIRSF000888 [1-378]T 0.0 PIRSF000888 Pesterase_HP1044 Pesterase_HP1044
noIPR
unintegrated
unintegrated
G3DSA:3.60.21.10 [157-325]T 1.79999951654676E-8 G3DSA:3.60.21.10 G3DSA:3.60.21.10 G3DSA:3.60.21.10
SSF56300 [157-375]T 9.1E-30 SSF56300 SSF56300 SSF56300


COGS Summary:  COGS Search
BeTs to 7 clades of COG1408
COG name: Predicted phosphohydrolases
Functional Class: R
The phylogenetic pattern of COG1408 is --t--q--eBr-uj----in-
Number of proteins in this genome belonging to this COG is 1
Blocks Summary:  Blocks Search
No significant hit to the Blocks database.

 ProDom Summary:  Protein Domain Search
Residues 275-374 are 42% similar to a (PROTEIN CONSERVED INTERGENIC REGION) protein domain (PD007404 which is seen in Q9ZM43_BBBBB.


Paralogs:  Local Blast Search
No paralogs found in P. gingivalis.

Pfam Summary:  Pfam Search
Residues 157 to 321 (E-value = 2.2e-13) place PG0005 in the Metallophos family which is described as Calcineurin-like phosphoesterase (PF00149)

 Structural Feature(s):
Feature Type  Start  Stop
transmembrane  
3  
19
transmembrane  
36  
52
transmembrane  
37  
54
transmembrane  
63  
87
transmembrane  
73  
89
transmembrane  
113  
129
transmembrane  
116  
133
coil-coil  
207  
242
transmembrane  
354  
371

Top PDB Hits:
No significant hits to the PDB database (E-value < E-10).

Gene Protein Sequence:
MKVFLEAFLLQYLLTLYIAYRGGQALPQKSLWRKGFHLLMGVVFTLYLIG
FAGNRVLPDAVMSCIMSVTGFWFVMSIYAMFAMVIVEIARVVDKRFLHRF
DRLSERVQARIRLGLFVLIGLSSALLVIHGLNIVRYPVVKHMDIRLDRPA
IDGRQSMKVALLTDIHISETVTAGHIREMVERTLAERPDIVLIGGDMIDY
HGRYARRDSITEYMRRLQDETPMGAYYVLGNHEYRADEVEKREWFRSIGH
LVIDQVVTPGNAFYLIGRDDSTNVFRAPLHKLMPHVDTTKASILLDHQPH
KLDSVAMTGVDLALYGHTHNGQIWPFTILTQLAFEKSWGYLRKGHTQFYV
SSGVGAAGPAIRVFTESEIVILNVRFASENKPVH

Gene Nucleotide Sequence:  Sequence Viewer
ATGAAAGTATTTCTCGAAGCCTTTCTCCTACAATATCTCCTGACCCTCTA
CATCGCATACCGAGGAGGACAGGCCCTACCGCAAAAGAGCCTTTGGCGCA
AAGGTTTTCACCTTCTGATGGGTGTAGTATTCACCCTGTATCTAATAGGG
TTTGCCGGCAACAGGGTTTTGCCCGATGCCGTGATGAGCTGCATTATGTC
TGTCACAGGCTTCTGGTTTGTCATGTCCATTTATGCCATGTTTGCCATGG
TGATCGTAGAGATTGCCCGTGTCGTGGACAAGCGTTTCCTGCACAGATTC
GACAGGCTGTCCGAAAGAGTGCAGGCTCGCATCCGATTGGGGCTGTTCGT
TCTCATAGGTTTGTCCTCGGCTTTACTCGTGATACATGGACTGAATATCG
TGCGCTATCCCGTTGTAAAGCATATGGACATTCGTCTGGACAGACCTGCC
ATAGATGGAAGGCAGTCCATGAAAGTAGCCCTGCTCACGGATATTCATAT
TAGCGAAACGGTGACGGCCGGCCATATCCGCGAGATGGTGGAGAGGACTT
TGGCCGAACGTCCGGATATTGTTCTGATCGGTGGGGATATGATCGACTAT
CATGGCAGGTATGCTCGTCGGGACAGCATCACGGAGTATATGCGCCGCCT
ACAGGATGAGACTCCCATGGGGGCTTACTATGTACTGGGCAATCATGAAT
ATAGGGCGGACGAAGTAGAGAAGCGCGAGTGGTTCCGTTCGATTGGCCAT
CTGGTGATCGATCAGGTTGTCACCCCGGGCAATGCATTCTATCTGATAGG
ACGGGACGATAGCACGAATGTATTCCGTGCTCCGCTGCACAAGCTTATGC
CACATGTCGATACCACTAAGGCCTCTATCCTGCTCGATCACCAGCCGCAC
AAGCTCGACAGCGTGGCGATGACCGGTGTGGACTTGGCTCTGTACGGGCA
CACGCACAACGGACAGATCTGGCCGTTTACGATTTTGACCCAACTGGCTT
TTGAAAAATCATGGGGCTATCTTCGCAAAGGGCATACGCAGTTCTATGTC
AGTTCAGGAGTAGGAGCGGCCGGACCGGCTATTCGTGTTTTCACGGAGAG
TGAGATCGTCATTCTGAATGTTCGGTTTGCCTCCGAAAACAAACCGGTTC
AT

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