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Porphyromonas gingivalis Search Results

Record: 1 of 1  
MiniMap tRNA-Gln-1 IGR0022 IGR0017 IGR0019 IGR0021 IGR0023 IGR0020 IGR0024 IGR0018 spoU, - PG0025 ychM, - PG0019 PG0019.1 cdd, - PG0026 ispF, - PG0024 PG0020 PG0021 PG0023 PG0022 spoU, - PG0025 ychM, - PG0019 PG0019.1 cdd, - PG0026 ispF, - PG0024 PG0020 PG0021 PG0023 PG0022 spoU, - PG0025 ychM, - PG0019 PG0019.1 cdd, - PG0026 ispF, - PG0024 PG0020 PG0021 PG0023 PG0022


LANL Gene ID: PG0022

GenBank Locus Tag: PG0026

DNA Molecule Name:
1  

GenBank ID:
34539903

Gene Name:


Definition:
conserved hypothetical protein

Cellular Location:
Outer membrane, Cytoplasm, Extracellular [Evidence]

Gene Start:
29374

Gene Stop:
32742

Gene Length:
3369

Molecular Weight*:
124502

pI*:
5.30

Net Charge*:
-23.63

EC:
 

Functional Class:
Unknown  

Gene Ontology:

Pathway: pathway table

Primary Evidence:
Check:

Proteases/Hemagglutinin Analysis

Zhang Y, Wang T, Chen W, Yilmaz O, Park Y, Jung IY, Hackett M, Lamont RJ.
Differential protein expression by Porphyromonas gingivalis in response to secreted epithelial cell components.
Proteomics. 2005 Jan;5(1):198-211.
PMID: 15619293

Comment:
TIGR ID: PG0026

Proteomic Data: Proteomic Data Search
TIGR Annotationhypothetical protein, GroupK (hypothetical proteins)
ORF #PG-PP/PG-PPC1PG-PP/PG-PPC2
Spectral CountPeptide IntensitySpectral CountPeptide Intensity
ProqValProqValProqValProqVal
TIGRPG0026-1.365.8e-06-1.486.7e-07-0.979.5e-05-1.486.7e-07
LANLPG00220.390.360.510.40
ConsensusSP1IP1SP2IP2

Human Oral Microbiome Database:
View in HOMD Genome Viewer

 Blast Summary:  PSI-Blast Search
Numerous significant hits by the C-terminal residues in gapped BLAST to gingipain precursor proteins; e.g. residues 496-763 are 23% similar to residues 316-585 of CPG1_PORGI. No significant hits involving the N-terminal ~500 amino acids nor to the ~300 C-terminal amino acids.

 Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|34539903|ref|NP_904382.1|  hypothetical protein PG0026 [P...  2285   0.0  
 gi|150009174|ref|YP_001303917.1|  hypothetical protein BDI_2...   727   0.0  
 gi|154494061|ref|ZP_02033381.1|  hypothetical protein PARMER...   715   0.0  
 gi|124008749|ref|ZP_01693438.1|  Fjo24 [Microscilla marina A...   440   e-121
 gi|110639610|ref|YP_679820.1|  hypothetical protein CHU_3237...   428   e-117
 gi|86134150|ref|ZP_01052732.1|  hypothetical protein MED152_...   383   e-104
 gi|67940985|ref|ZP_00533271.1|  conserved hypothetical prote...   382   e-104
 gi|83596043|gb|ABC25401.1|  Fjo24, putative [uncultured mari...   367   2e-99
 gi|150025454|ref|YP_001296280.1|  Protein of unknown functio...   362   9e-98
 gi|86132115|ref|ZP_01050711.1|  hypothetical protein MED134_...   357   2e-96


InterPro Summary:  InterProScan

noIPR
unintegrated
unintegrated
G3DSA:3.40.50.1460 [524-754]T 1.1999906342192102E-75 G3DSA:3.40.50.1460 G3DSA:3.40.50.1460 G3DSA:3.40.50.1460
SSF52129 [362-756]T 1.4999999999999997E-95 SSF52129 SSF52129 SSF52129


COGS Summary:  COGS Search
No hit to the COGs database.
Blocks Summary:  Blocks Search
No significant hit to the Blocks database.

 ProDom Summary:  Protein Domain Search
No significant hit to the ProDom database.

Paralogs:  Local Blast Search
Residues 496-763 are 23% similar to the same domains (residues 318-587) in PG0461, gingipain R2, and in PG1768, gingipain R1.

Pfam Summary:  Pfam Search
No significant hits to the Pfam 11.0 database

 Structural Feature(s):
Feature Type  Start  Stop
No predicted structural features.  
  

Top PDB Hits:
-40% similar to PDB:1CVR CRYSTAL STRUCTURE OF THE ARG SPECIFIC CYSTEINE PROTEINASE GINGIPAIN R (RGPB) (E_value = 8.9E_10);
-45% similar to PDB:2GZA Crystal structure of the VirB11 ATPase from the Brucella Suis type IV secretion system in complex with sulphate (E_value = 8.9E_10);
-44% similar to PDB:1CM5 CRYSTAL STRUCTURE OF C418A,C419A MUTANT OF PFL FROM E.COLI (E_value = 8.9E_10);
-44% similar to PDB:1H16 PYRUVATE FORMATE-LYASE (E.COLI) IN COMPLEX WITH PYRUVATE AND COA (E_value = 8.9E_10);
-44% similar to PDB:1H17 PYRUVATE FORMATE-LYASE (E.COLI) IN COMPLEX WITH COA AND THE SUBSTRATE ANALOG OXAMATE (E_value = 8.9E_10);

Gene Protein Sequence:
MASGHWVKIRVDASGVYRLTDEQLRANGFSDPSKVGVFGYGGGVLPEDLS
RITTDDLPPVPVLRQGNALYFYAVGPVTWFYNPAKTTMEHTVNTYSTHGY
YFLSDAAGAPLQMSQYTGGGASAEALIDYYDELMLHEQELYSPKESGRDL
YGESFSAVNTRTVKFPLRGNTRSSGELGTVFSYIAKARSAGGGREMSLSA
NGILIFSDPFSMTSNEVSNSYLAGKKRRLYHSTPMNSLVNELRLDANYSM
TGDAVNLDFIEVATQNDLRYDGAPMHIRRFSNLPVLGGESCRFVISEVPE
SLVVLQANSSLTASLVPVKTVGDKTIEFVAPPKGQDRRTINTFYAVDLSQ
ASAPEILGAVPNQNLHGEEIPDLIIVSTQALLLEADRLATYRREKNGLKV
LVVLQEQVFNEFSGGTPDATAYRLFAKMFYDRWKANAPVGETFPMQMLLF
GDGAHDNRKVSVAWQKPYLQQTEFLLTFQAVNSTNVNSYVTDDYFGLLDD
QPASVNIGWRNYNMAVGRFPVRTPAEARIAVDKTIRYEEDRESGAWRIRA
CFAADNGDKHATETSRLIDTVKRYAPAIMPVRAFQDVYPHVIENGLHSIP
GAKKKMLETLQSGIILLNYAGHGGPAGWSDEHLLTLNDIHKFNYKHMPIW
ITATCDFANYDSQTTSAGEEVFLHEKSGTPIMFSTTRVVYNTQNEKINGF
MLRRMFEKAKDGRYRTMGEIIRSAKQGMLSTVFPDSINQLSFFLMGDPSV
RMNLPTHKVQLTAINGQDPEGQYGTIMLKSLERVALKGKVTDEKGTFDET
FSGKVFLTVFDGRKKMTALEEEGNDLSLVYYDYPNVMYAGIAEVKDGLFE
TSFIVPKDVNYSEHEGRINLYAYNESTKAEAMGVDFSIRVQPGIPDEVTE
DNTPPEIISCFLNDSTFRSGDEVNPTPLFMAEVFDLNGINITGSGVGHDI
TLCIDGRADLTYNLNAYFTSSATDAGVGTILFMIPALAEGDHTARLTVWD
IFNNAVHHDFSFRVVDGIAPDVADVILFPNPVRESATFRIFHNRPGSDLN
VAVEIYDFTGRLVNSLPVKTYSSSYGEPIEIKWDLTSKYGVKIGNGFYLY
RCVVNSPGGQTASMAKKMIVVGQ

Gene Nucleotide Sequence:  Sequence Viewer
ATGGCTTCGGGACATTGGGTCAAGATACGTGTCGATGCAAGTGGAGTGTA
TCGCCTTACGGACGAACAGCTCCGTGCCAATGGCTTCTCCGATCCGTCCA
AGGTAGGTGTGTTCGGTTATGGTGGAGGGGTGCTTCCCGAAGATCTGAGC
CGGATCACGACAGACGATTTGCCTCCGGTACCGGTACTCCGTCAGGGCAA
TGCGCTGTATTTCTATGCCGTGGGCCCGGTGACATGGTTCTACAATCCGG
CCAAAACCACCATGGAGCATACGGTGAATACATACAGTACGCATGGCTAC
TACTTCCTGTCGGATGCTGCCGGAGCACCTTTGCAGATGTCCCAATATAC
GGGTGGAGGTGCGTCGGCCGAGGCTTTGATCGACTACTACGATGAGCTGA
TGCTCCATGAACAGGAATTGTATTCGCCCAAAGAATCGGGACGAGATCTG
TATGGCGAGTCTTTCAGTGCAGTCAATACGCGTACGGTCAAGTTCCCTTT
GAGGGGCAACACCCGCTCGTCTGGCGAACTCGGTACCGTATTCTCATACA
TAGCCAAGGCCAGATCGGCCGGTGGCGGCCGTGAGATGTCGCTCTCGGCG
AATGGCATTCTGATCTTCAGCGATCCTTTTTCCATGACATCGAATGAAGT
CTCCAATTCCTATTTGGCCGGCAAGAAGCGTCGTCTCTATCACAGTACGC
CGATGAACAGCTTGGTCAATGAGTTGCGCTTGGACGCGAACTATAGCATG
ACAGGAGATGCGGTCAATCTGGATTTCATAGAGGTGGCTACACAGAACGA
CCTCCGGTACGATGGCGCACCCATGCATATCAGGCGGTTTTCCAATTTGC
CCGTTTTGGGGGGCGAGTCCTGCCGGTTCGTTATCAGTGAGGTGCCGGAG
TCTCTGGTGGTTTTGCAGGCCAATTCTTCCCTGACAGCATCGCTTGTTCC
CGTTAAGACTGTCGGGGATAAGACCATTGAGTTCGTGGCTCCGCCGAAGG
GTCAGGATCGTAGGACTATCAATACGTTTTATGCCGTGGACTTGTCACAG
GCTTCTGCTCCGGAGATCCTCGGAGCGGTACCCAATCAAAACCTGCATGG
AGAGGAAATCCCTGATCTGATCATTGTCTCTACTCAGGCGCTCCTCCTTG
AGGCTGATCGACTGGCCACCTATCGTAGAGAGAAAAACGGGCTGAAGGTT
TTGGTCGTGTTGCAGGAACAGGTGTTCAACGAGTTTTCGGGTGGAACTCC
CGATGCTACAGCATACCGCCTCTTTGCCAAAATGTTCTACGACAGATGGA
AGGCAAATGCACCTGTGGGAGAGACCTTCCCGATGCAAATGCTTCTCTTC
GGTGATGGGGCTCATGACAACAGGAAGGTCTCCGTAGCTTGGCAGAAACC
GTATCTCCAACAAACGGAGTTCTTGCTGACATTCCAAGCCGTCAATTCGA
CGAACGTAAACAGTTATGTGACGGATGATTACTTCGGCTTGCTGGATGAT
CAGCCGGCCTCGGTCAATATCGGTTGGCGCAATTATAATATGGCTGTAGG
GCGATTCCCCGTACGTACTCCGGCCGAAGCTCGCATCGCAGTGGACAAGA
CCATCCGATATGAGGAGGATCGAGAGAGTGGTGCCTGGCGTATTCGTGCC
TGTTTTGCGGCAGACAACGGGGACAAGCACGCAACCGAGACTTCCCGTTT
GATCGATACCGTCAAGCGTTATGCTCCTGCCATCATGCCGGTACGCGCCT
TTCAGGACGTATATCCGCATGTCATCGAGAACGGGTTGCACAGCATTCCG
GGTGCAAAGAAAAAGATGCTGGAAACCCTTCAGTCGGGTATTATCCTGCT
TAATTATGCTGGTCATGGCGGTCCTGCCGGATGGTCGGACGAGCATTTGC
TGACGCTCAACGATATACACAAATTCAATTATAAGCATATGCCCATTTGG
ATTACTGCCACGTGCGACTTTGCCAACTATGACAGTCAGACGACCTCGGC
AGGGGAGGAGGTTTTCCTCCATGAGAAGAGTGGCACTCCGATCATGTTCT
CGACTACGCGTGTCGTTTACAATACGCAGAATGAGAAGATCAATGGTTTT
ATGCTTCGGCGTATGTTCGAGAAAGCTAAGGATGGGCGTTATCGTACGAT
GGGCGAGATTATCCGATCGGCCAAACAGGGGATGCTCAGTACTGTTTTCC
CCGATTCGATCAACCAGTTGAGTTTCTTTCTGATGGGTGATCCGTCCGTG
CGTATGAATCTTCCTACCCACAAAGTGCAATTGACCGCAATCAACGGGCA
GGATCCCGAAGGGCAGTATGGAACTATTATGCTCAAGTCTTTGGAACGGG
TAGCTCTGAAGGGTAAGGTAACCGATGAAAAGGGGACATTCGACGAGACA
TTCAGTGGCAAGGTTTTCCTGACCGTCTTCGATGGCAGAAAGAAAATGAC
AGCTTTGGAAGAGGAGGGAAACGATCTCTCTCTTGTATATTATGACTATC
CTAACGTGATGTATGCCGGTATTGCCGAGGTGAAAGACGGACTCTTCGAA
ACTTCGTTTATCGTACCCAAGGATGTGAACTATTCCGAGCACGAAGGCCG
GATCAATCTTTATGCTTATAACGAGAGCACAAAGGCGGAAGCCATGGGGG
TAGACTTCTCCATCAGAGTCCAACCGGGTATTCCTGATGAGGTAACGGAA
GATAATACACCGCCTGAAATCATAAGCTGCTTCCTCAATGACAGTACATT
CCGATCGGGAGATGAGGTTAATCCTACTCCTCTGTTTATGGCCGAAGTAT
TCGACTTGAATGGAATCAATATCACGGGTAGCGGAGTAGGGCATGATATT
ACGCTTTGTATCGATGGCCGTGCCGACCTGACCTACAACCTCAATGCATA
TTTCACAAGTTCGGCTACGGATGCAGGTGTGGGCACTATTCTCTTCATGA
TACCGGCTTTGGCCGAAGGAGATCATACTGCCCGACTGACGGTTTGGGAC
ATTTTCAATAATGCCGTCCATCATGACTTTTCATTCAGAGTGGTAGATGG
CATTGCTCCGGATGTGGCTGATGTGATTCTATTCCCGAATCCGGTACGCG
AGAGTGCTACGTTCCGAATCTTCCACAATCGCCCCGGAAGCGATTTGAAC
GTGGCCGTGGAGATCTATGACTTCACCGGTCGTCTTGTGAACAGTTTGCC
AGTCAAGACCTATTCGTCTTCCTACGGAGAACCTATAGAGATCAAGTGGG
ATCTGACCTCCAAATACGGAGTGAAGATCGGAAACGGATTCTACCTCTAT
CGTTGTGTGGTGAACTCTCCCGGAGGACAGACGGCCTCCATGGCCAAGAA
AATGATCGTGGTAGGACAA

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