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Porphyromonas gingivalis Search Results

Record: 1 of 1  
MiniMap IGR0055 IGR0051 IGR0052 IGR0054 IGR0050 IGR0053 PG0057 lpxA, - PG0059 czcB, - PG0056 PG0054 fabZ, - PG0060 PG0058 czcA, - PG0055 PG0053 PG0057 lpxA, - PG0059 czcB, - PG0056 PG0054 fabZ, - PG0060 PG0058 czcA, - PG0055 PG0053 PG0057 lpxA, - PG0059 czcB, - PG0056 PG0054 fabZ, - PG0060 PG0058 czcA, - PG0055 PG0053


LANL Gene ID: PG0056

GenBank Locus Tag: PG0065

DNA Molecule Name:
1  

GenBank ID:
34539937

Gene Name:
czcB  

Definition:
conserved hypothetical protein (possible membrane fusion protein) (possible cation efflux membrane fusion protein)

Cellular Location:
Outer membrane, Inner membrane, Extracellular [Evidence]

Gene Start:
81277

Gene Stop:
80306

Gene Length:
972

Molecular Weight*:
35115

pI*:
6.30

Net Charge*:
-2.63

EC:
 

Functional Class:
Transport and binding; Cations  

Gene Ontology:
Biological process
  GO:0009306    protein secretion

Cellular component
  GO:0016020    membrane

Molecular function
  GO:0008565    protein transporter activity


Pathway: pathway table

Comment:
TIGR ID: PG0065

Human Oral Microbiome Database:
View in HOMD Genome Viewer

Blast Summary:  PSI-Blast Search
Several weak hits in gapped BLAST to hypothetical proteins, putative membrane proteins, and metal cation efflux membrane proteins, e.g. residues 46-318 are 25% similar to (AP002560) putative membrane protein of E. coli, residues 46-318 are 25% similar to (P76397) hypothetical protein of E. coli,
residues 10-322 are 24% similar to the metal cation efflux membrane protein, czcB protein, from Pseudomonas aeruginosa (AE004679).

This sequence is similar to BT2038.

Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|34539937|ref|NP_904416.1|  efflux transporter, RND family...   588   e-166
 gi|53713380|ref|YP_099372.1|  cation efflux system protein [...   395   e-108
 gi|53715006|ref|YP_100998.1|  cation efflux system protein [...   340   6e-92
 gi|150008240|ref|YP_001302983.1|  cation efflux system prote...   340   7e-92
 gi|60682969|ref|YP_213113.1|  putative metal resistance rela...   340   8e-92
 gi|150004578|ref|YP_001299322.1|  putative metal resistance ...   337   8e-91
 gi|29347448|ref|NP_810951.1|  cation efflux system protein [...   331   4e-89
 gi|153808890|ref|ZP_01961558.1|  hypothetical protein BACCAC...   328   2e-88
 gi|156111888|gb|EDO13633.1|  hypothetical protein BACOVA_006...   326   1e-87
 gi|154492605|ref|ZP_02032231.1|  hypothetical protein PARMER...   325   3e-87


InterPro Summary:  InterProScan

InterPro
IPR006143
Family
Secretion protein HlyD
TIGR01730 [3-318]T 5.3e-32 TIGR01730 RND_mfp: efflux transporter, RND family, MF RND_mfp: efflux transporter, RND family, MF


COGS Summary:  COGS Search
BeTs to 7 clades of COG0845
COG name: Membrane permeases, predicted cation efflux pumps
Functional Class: R
The phylogenetic pattern of COG0845 is -----QvCEB-hUJ--ol--x
Number of proteins in this genome belonging to this COG is 6
Blocks Summary:  Blocks Search
No significant hit to the Blocks database.

 ProDom Summary:  Protein Domain Search
Residues 137-306 are 27% similar to a (PROTEIN MEMBRANE RESISTANCE PRECURSOR) protein domain (PD000988 which is seen in YEGM_ECOLI.


Paralogs:  Local Blast Search
Residues 22-3069 are 22% similar to PG0492, a cation efflux membrane fusion protein. Residues 131-302 are 24%) similar to PG0257, membrane permease. Residues 1-303 are 18% similar to PG0612, possible membrane permease. Residues 27-301 are 25% similar to PG1454, putative periplasmic protein.

Pfam Summary:  Pfam Search
No significant hits to the Pfam 11.0 database

 Structural Feature(s):
Feature Type  Start  Stop
cleavable signal  
1  
37
coil-coil  
72  
120

Top PDB Hits:
-42% similar to PDB:1T5E The structure of MexA (E_value = 9.6E_11);
-42% similar to PDB:1VF7 Crystal structure of the membrane fusion protein, MexA of the multidrug transporter (E_value = 9.6E_11);

Gene Protein Sequence:
LQVEEVAPASFNYVIKTSGQILSAQGDEATIAATANGIVSFAGSAFTEGA
SVRAGECIVRISAKNLPDGDPVTKAKIAYESAQKEHRRAEKLVKDQIISN
KEYEQTCRDYQTAKTIYEAQASGTGAGGVSVASPMSGYIKNRMVNQGEYV
SVGQPIATVSQNRRLQLRAEVSESHFKNVRNVSGANFQTSYDNKLYELSD
LNGRLLSFGRASTQSSYIPVTFEFDNVGDVVPGSFVTVYLLSNTQEEVLS
VPVSAITEEQGLHFVYLRLAEEEYQKQEVTLGQSNGRRVRILSGLKAGDN
VVTHGVYQVKLAATSSVMPEGHTH

Gene Nucleotide Sequence:  Sequence Viewer
TTGCAGGTAGAGGAAGTGGCACCTGCCTCTTTCAACTATGTGATCAAAAC
AAGCGGACAGATCCTCTCCGCCCAAGGCGATGAAGCCACCATAGCAGCTA
CGGCCAACGGCATCGTTTCGTTTGCCGGTTCGGCCTTTACAGAAGGAGCC
TCCGTACGAGCAGGAGAGTGCATCGTACGCATCTCTGCCAAAAATCTGCC
GGATGGAGATCCCGTAACCAAGGCAAAGATCGCTTACGAATCGGCTCAAA
AGGAACACCGGCGGGCTGAAAAGCTGGTAAAAGATCAGATCATTTCGAAC
AAGGAATACGAACAGACTTGCAGGGACTATCAGACAGCCAAGACCATATA
CGAAGCCCAAGCATCCGGCACCGGTGCGGGAGGGGTCAGCGTGGCGTCTC
CTATGAGCGGATATATCAAAAACCGCATGGTCAACCAGGGCGAATACGTA
TCCGTAGGCCAACCCATAGCCACCGTGTCACAAAACCGCCGGTTGCAGCT
ACGGGCGGAGGTATCGGAGAGCCATTTCAAGAATGTCCGCAATGTCTCCG
GTGCCAACTTCCAGACTTCATACGACAACAAGCTCTACGAGCTGTCCGAT
CTGAACGGAAGGCTGCTCTCGTTCGGGCGTGCATCCACACAGTCATCCTA
CATCCCCGTTACATTCGAATTCGACAATGTGGGCGATGTCGTACCCGGCT
CTTTCGTCACTGTGTATCTGCTCTCCAATACTCAGGAAGAAGTTCTCTCC
GTTCCCGTATCGGCCATTACCGAAGAGCAGGGATTGCACTTCGTCTATCT
GCGGTTGGCCGAAGAGGAGTATCAGAAACAAGAGGTTACCCTCGGGCAGA
GCAACGGACGTCGTGTGCGAATCCTGTCCGGACTGAAAGCCGGAGACAAT
GTTGTGACTCATGGAGTATATCAGGTGAAACTGGCCGCTACTTCGTCCGT
AATGCCTGAAGGTCATACTCAC

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