Basic Search | Intermediate Search | Advanced Search | Gene Image Map |  Sequence Search |  Protein Motif Search |  Repeat Search |  DNA/RNA Motif Search |  Home

Porphyromonas gingivalis Search Results

Record: 1 of 1  
MiniMap IGR0066 IGR0072 IGR0064 IGR0071 IGR0065 IGR0067 IGR0069 IGR0068 IGR0070 PG0076 PG0081 PG0080 PG0074 PG0078 dps, - PG0079 sda,sdh, - PG0072 PG0077 melA, - PG0073 PG0076 PG0081 PG0080 PG0074 PG0078 dps, - PG0079 sda,sdh, - PG0072 PG0077 melA, - PG0073 Type: tandem, Name: tan33 - 241 Type: tandem, Name: tan34 - 242 Type: tandem, Name: tan84 - 292 PG0076 PG0081 PG0080 PG0074 PG0078 dps, - PG0079 sda,sdh, - PG0072 PG0077 melA, - PG0073


LANL Gene ID: PG0076

GenBank Locus Tag: PG0087

DNA Molecule Name:
1  

GenBank ID:
34539957

Gene Name:


Definition:
SIS domain protein

Cellular Location:
Cytoplasm [Evidence]

Gene Start:
103215

Gene Stop:
102598

Gene Length:
618

Molecular Weight*:
22086

pI*:
5.90

Net Charge*:
-4.46

EC:
 

Functional Class:
Unassigned  

Gene Ontology:
Biological process
  GO:0005975    carbohydrate metabolic process

Molecular function
  GO:0005529    sugar binding


Pathway: pathway table

Secondary Evidence:
Bateman A.
The SIS domain: a phosphosugar-binding domain.
Trends Biochem Sci. 1999 Mar;24(3):94-5.
PMID: 10203754

Comment:
TIGR ID: PG0087

From InterPro: IPR001347    
Sugar isomerase (SIS)

The SIS (Sugar ISomerase) domain is a phosphosugar-binding domain found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars possibly by binding to the end-product of the pathway.

Proteomic Data: Proteomic Data Search
TIGR AnnotationSIS domain protein, GroupT (unknown function)
ORF #PG-PP/PG-PPC1PG-PP/PG-PPC2
Spectral CountPeptide IntensitySpectral CountPeptide Intensity
ProqValProqValProqValProqVal
TIGRPG0087-0.840.081-0.240.2-1.310.0061-0.240.2
LANLPG00760.560.850.400.95
ConsensusSP1IP1SP2IP2

Human Oral Microbiome Database:
View in HOMD Genome Viewer

 Blast Summary:  PSI-Blast Search
This sequence corresponds to 34396268 in Genbank.

Its nearest neighbor in the NR database is 29340621 from Bacteroides thetaiotaomicron VPI-5482.


 Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|34539957|ref|NP_904436.1|  SIS domain protein [Porphyromo...   379   e-104
 gi|154490033|ref|ZP_02030294.1|  hypothetical protein PARMER...   273   5e-72
 gi|150009487|ref|YP_001304230.1|  putative sugar isomerase [...   261   1e-68
 gi|156111631|gb|EDO13376.1|  hypothetical protein BACOVA_009...   250   4e-65
 gi|153807210|ref|ZP_01959878.1|  hypothetical protein BACCAC...   248   1e-64
 gi|156861946|gb|EDO55377.1|  hypothetical protein BACUNI_010...   248   2e-64
 gi|29348715|ref|NP_812218.1|  putative sugar isomerase [Bact...   247   3e-64
 gi|53711463|ref|YP_097455.1|  putative sugar isomerase [Bact...   242   9e-63
 gi|150003839|ref|YP_001298583.1|  putative sugar isomerase [...   236   8e-61
 gi|52841076|ref|YP_094875.1|  polysialic acid capsule expres...   160   5e-38


InterPro Summary:  InterProScan

InterPro
IPR001347
Domain
Sugar isomerase (SIS)
PF01380 [47-176]T 3.1999989904635494E-19 PF01380 SIS SIS
noIPR
unintegrated
unintegrated
G3DSA:3.40.50.10490 [4-191]T 2.10000267834025E-34 G3DSA:3.40.50.10490 G3DSA:3.40.50.10490 G3DSA:3.40.50.10490
SSF53697 [4-199]T 1.5E-39 SSF53697 SSF53697 SSF53697


COGS Summary:  COGS Search
BeTs to 10 clades of COG0794
COG name: Predicted sugar phosphate aminotransferases involved in capsule formation
Functional Class: M
The phylogenetic pattern of COG0794 is amTk-q-cEb-huj----inx
Number of proteins in this genome belonging to this COG is 1
Blocks Summary:  Blocks Search
No significant hit to the Blocks database.

 ProDom Summary:  Protein Domain Search
Residues 71-152 are 46% similar to a (PROTEIN AMINOTRANSFERASE) protein domain (PD000868 which is seen in YRBH_ECOLI.


Paralogs:  Local Blast Search
No paralogs found in P. gingivalis.

Pfam Summary:  Pfam Search
Residues 39 to 175 (E-value = 3.1e-21) place PG0076 in the SIS family which is described as SIS domain (PF01380)

 Structural Feature(s):
Feature Type  Start  Stop
No predicted structural features.  
  

Top PDB Hits:
No significant hits to the PDB database (E-value < E-10).

Gene Protein Sequence:
MKAEIHNRTISEILAHEAEAIRTIPADNDYKAAIDLIVRQVHGSNGRLIT
SGMGKAGQIAANIATTFSSTGTPAYFLHPSEAQHGDLGLVRSGDIMLLIS
NSGRTREVLELVELTKRLVPDTKFILITGNPESQLAAEVDVCLATGNPAE
VCPLGMTPTTSTTVMTVIGDVLVVGTMQEIGFGFEDYARRHHGGYLGDRS
REICGR

Gene Nucleotide Sequence:  Sequence Viewer
ATGAAGGCAGAAATACACAATCGAACCATCTCCGAAATACTGGCACATGA
AGCTGAAGCCATCCGTACCATCCCTGCAGACAACGACTATAAGGCGGCTA
TCGACCTCATTGTTCGTCAAGTGCATGGCTCTAACGGTCGGCTGATAACT
TCGGGTATGGGCAAGGCCGGACAGATTGCTGCCAACATAGCCACGACTTT
CAGTTCCACCGGTACTCCCGCATACTTCCTTCACCCGAGCGAAGCCCAGC
ATGGCGATTTGGGTTTGGTGCGTAGCGGTGATATTATGCTTCTGATCAGC
AATTCGGGGCGAACGCGCGAAGTACTGGAGTTGGTAGAGCTGACCAAACG
CTTGGTTCCCGATACGAAATTCATCCTCATTACAGGCAACCCCGAGAGCC
AGCTTGCGGCGGAGGTGGATGTCTGCCTGGCCACCGGCAATCCGGCCGAA
GTATGTCCTTTGGGAATGACTCCGACTACCAGTACGACGGTGATGACAGT
GATCGGCGATGTTCTGGTCGTAGGTACGATGCAGGAGATCGGCTTCGGCT
TCGAGGATTATGCACGTCGCCATCACGGCGGTTATCTTGGCGACAGAAGT
CGCGAAATATGTGGGCGA

Los Alamos National Laboratory • Est 1943

Operated by Los Alamos National Security, LLC for the U.S. Department of Energy's National Nuclear Security Administration
Inside | © Copyright 2006 LANS LLC All rights reserved | Disclaimer/Privacy