Basic Search | Intermediate Search | Advanced Search | Gene Image Map |  Sequence Search |  Protein Motif Search |  Repeat Search |  DNA/RNA Motif Search |  Home

Porphyromonas gingivalis Search Results

Record: 1 of 1  
MiniMap IGR0073 IGR0074 IGR0072 IGR0071 IGR0076 IGR0070 IGR0075 PG0085 PG0082 PG0081 PG0080 PG0083 mutS, - PG0084 dps, - PG0079 PG0085 PG0082 PG0081 PG0080 PG0083 mutS, - PG0084 dps, - PG0079 PG0085 PG0082 PG0081 PG0080 PG0083 mutS, - PG0084 dps, - PG0079


LANL Gene ID: PG0083

GenBank Locus Tag: PG0094

DNA Molecule Name:
1  

GenBank ID:
34539963

Gene Name:


Definition:
conserved hypothetical protein (possible alkaline secretion protease)

Cellular Location:
Outer membrane, Cytoplasm [Evidence]

Gene Start:
111283

Gene Stop:
109781

Gene Length:
1503

Molecular Weight*:
55598

pI*:
7.70

Net Charge*:
2.55

EC:
 

Functional Class:
Unknown; Conserved hypothetical  

Gene Ontology:
Biological process
  GO:0006810    transport

Molecular function
  GO:0005215    transporter activity


Pathway: pathway table

Comment:
TIGR ID: PG0094

Proteomic Data: Proteomic Data Search
TIGR Annotationouter membrane efflux protein, putative, GroupS (transport and binding proteins)
ORF #PG-PP/PG-PPC1PG-PP/PG-PPC2
Spectral CountPeptide IntensitySpectral CountPeptide Intensity
ProqValProqValProqValProqVal
TIGRPG0094-1.477.9e-10-1.840.00021-0.290.1-1.840.00021
LANLPG00830.360.280.820.56
ConsensusSP1IP1SP2IP2

Human Oral Microbiome Database:
View in HOMD Genome Viewer

 Blast Summary:  PSI-Blast Search
Several weak hits in gapped BLAST to hypothetical proteins, possible lipases, alkaline proteases: residues 22-462 are 39% similar to jhp1382 from Helicobacter pylori (AE001560). Residues 98-469 are 38% similar to APRF_PSEAE, an alkaline secretion protease.

This sequence is similar to BT3905.

 Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|34539963|ref|NP_904442.1|  outer membrane efflux protein,...   934   0.0  
 gi|153809121|ref|ZP_01961789.1|  hypothetical protein BACCAC...   573   e-162
 gi|156111384|gb|EDO13129.1|  hypothetical protein BACOVA_011...   573   e-161
 gi|29349313|ref|NP_812816.1|  putative alkaline protease apr...   562   e-158
 gi|53715268|ref|YP_101260.1|  putative alkaline protease Apr...   538   e-151
 gi|156859684|gb|EDO53115.1|  hypothetical protein BACUNI_031...   537   e-151
 gi|154493623|ref|ZP_02032943.1|  hypothetical protein PARMER...   422   e-116
 gi|150006809|ref|YP_001301552.1|  putative alkaline protease...   414   e-113
 gi|153808818|ref|ZP_01961486.1|  hypothetical protein BACCAC...   192   6e-47
 gi|150006606|ref|YP_001301350.1|  putative outer membrane pr...   188   9e-46


InterPro Summary:  InterProScan

InterPro
IPR003423
Family
Outer membrane efflux protein
PF02321 [105-280]T 0.6399999948701579 PF02321 OEP[305-491]T 1.1000015067164302E-22 PF02321 OEP OEP
noIPR
unintegrated
unintegrated
SSF56954 [23-496]T 4.3000000000000005E-76 SSF56954 SSF56954 SSF56954


COGS Summary:  COGS Search
BeTs to 4 clades of COG1538
COG name: Putative outer membrane protein
Functional Class: S
The phylogenetic pattern of COG1538 is -----Q-c----uj------x
Number of proteins in this genome belonging to this COG is 4
Blocks Summary:  Blocks Search
No significant hit to the Blocks database.

 ProDom Summary:  Protein Domain Search
Residues 23-462 are 22% similar to a (PROTEIN LIPASE-LIKE PUTATIVE) protein domain (PD143779 which is seen in Q9ZJD0_BBBBB.


Paralogs:  Local Blast Search
PG0083 show weak similarity to PG1455, PG0490, PG0611, PG0259, all of which are weakly related to APRF_PSEAE, an alkaline protease secretion protein. See BLAST Summary.

Pfam Summary:  Pfam Search
Residues 305 to 491 (E-value = 1.5e-25) place PG0083 in the OEP family which is described as Outer membrane efflux protein (PF02321)

 Structural Feature(s):
Feature Type  Start  Stop
uncleavable signal  
1  
13
transmembrane  
4  
20
coil-coil  
212  
239
coil-coil  
388  
447

Top PDB Hits:
-42% similar to PDB:2B78 A putative sam-dependent methyltransferase from Streptococcus mutans (E_value = );
-42% similar to PDB:1A2Q SUBTILISIN BPN' MUTANT 7186 (E_value = );
-42% similar to PDB:1LW6 Crystal Structure of the Complex of Subtilisin BPN' with Chymotrypsin Inhibitor 2 at 1.5 Angstrom Resolution (E_value = );
-42% similar to PDB:1S02 EFFECTS OF ENGINEERED SALT BRIDGES ON THE STABILITY OF SUBTILISIN BPN' (E_value = );
-42% similar to PDB:1SBN REFINED CRYSTAL STRUCTURES OF SUBTILISIN NOVO IN COMPLEX WITH WILD-TYPE AND TWO MUTANT EGLINS. COMPARISON WITH OTHER SERINE PROTEINASE INHIBITOR COMPLEXES (E_value = );

Gene Protein Sequence:
MKRLIIAGVLACALWPVYGQRVLSVNECRRLALEHNRDLAISREKINAAT
STRKAAFTSYLPELSATGTYLHNQKEVSLLSDEQKHKLQNLGTDLVTAIG
QNPYITTAIQSILAQHPDLAPLIGSMMPQIATQTSQGLNAFGTHLVDAVR
TDTRNVYAGVLTLTQPLYVGGKIYAYNRITRYAEEIAHWQHKTGQQDVIL
ATDQAYWQVVSLANKHRLAESYLELLTKLDNDVQKLIKEGLATRADGLNV
SVKVNEAEMTLAKVEDGLSLSRMLLCQTIGLPLDETITLADEGQEELPTT
IVPAETDLQYTLDNRPELKSLALLEQISKQKIRLTRSEYLPSLAFVANYL
VTNPSSFNGFENKFGGMWNVGVMLKVPIWHWGQGTHKVRAAKAEARIAAQ
QLAKARESIELQLSQSVLKVREADKRLVMATKNMEKAEENLRYANVGFRE
GVITASNVLEAQTAWLSARSAKIDAQIDVKLTELMLRKASGHLSPEEVVS
E

Gene Nucleotide Sequence:  Sequence Viewer
ATGAAACGATTGATTATCGCAGGCGTTTTGGCATGCGCCTTGTGGCCGGT
ATATGGACAGAGAGTACTGAGCGTGAACGAATGCCGGCGCCTTGCCCTCG
AACACAACAGAGACTTGGCCATAAGCCGCGAAAAGATAAATGCGGCCACC
AGTACTCGCAAAGCCGCTTTCACCAGCTACCTGCCCGAGCTCTCGGCCAC
CGGTACTTACCTGCACAACCAGAAGGAAGTATCGCTATTGAGCGACGAGC
AGAAGCACAAGCTCCAGAATCTCGGCACCGACCTTGTCACAGCCATAGGG
CAGAATCCCTACATCACGACGGCTATTCAGTCCATCCTTGCCCAGCATCC
CGATTTGGCTCCCCTTATCGGATCCATGATGCCGCAGATAGCCACCCAGA
CGAGTCAGGGGCTTAACGCCTTCGGTACACACCTCGTCGATGCCGTGCGC
ACCGATACCCGCAATGTCTATGCCGGTGTGCTGACCCTGACCCAACCGCT
GTATGTAGGCGGCAAGATATATGCCTACAACCGCATCACGCGCTATGCCG
AAGAGATAGCACACTGGCAGCACAAGACCGGACAGCAGGATGTGATCCTC
GCTACCGACCAGGCCTATTGGCAAGTGGTTTCTTTGGCCAATAAGCACCG
CCTTGCCGAGAGCTATCTGGAGTTGCTGACGAAGCTCGACAACGATGTCC
AGAAGCTCATCAAGGAGGGATTGGCTACCCGTGCCGACGGTCTCAACGTA
TCGGTAAAGGTGAACGAAGCGGAGATGACGCTCGCTAAGGTAGAGGATGG
GCTTAGCCTCTCGCGCATGCTTCTGTGCCAAACGATAGGACTGCCCCTCG
ACGAGACGATCACCCTCGCAGACGAAGGGCAAGAGGAGTTGCCGACGACC
ATCGTTCCGGCAGAGACCGACCTGCAATACACCCTCGACAACCGTCCCGA
ACTCAAGAGTCTCGCCCTGTTAGAGCAAATCTCCAAACAGAAGATACGGC
TTACACGATCGGAATATCTGCCATCGCTCGCCTTCGTTGCCAACTATTTA
GTGACTAATCCGTCCTCTTTCAATGGTTTCGAGAATAAATTCGGAGGTAT
GTGGAATGTGGGTGTGATGCTCAAAGTTCCTATCTGGCACTGGGGGCAGG
GCACGCATAAGGTAAGAGCGGCCAAAGCCGAGGCACGCATCGCAGCCCAA
CAACTTGCCAAAGCACGCGAAAGCATCGAGCTACAGCTCTCCCAAAGCGT
CCTGAAAGTACGGGAGGCAGACAAACGACTTGTCATGGCCACGAAGAACA
TGGAGAAAGCCGAAGAGAACCTGCGCTATGCCAATGTAGGTTTCCGCGAA
GGCGTAATAACGGCCTCCAACGTACTGGAAGCTCAGACGGCATGGTTGTC
GGCCCGGTCTGCAAAGATCGATGCACAGATCGACGTGAAACTGACCGAAC
TGATGCTGCGCAAGGCTTCGGGACACCTCTCCCCGGAAGAAGTCGTTTCG
GAA

Los Alamos National Laboratory • Est 1943

Operated by Los Alamos National Security, LLC for the U.S. Department of Energy's National Nuclear Security Administration
Inside | © Copyright 2006 LANS LLC All rights reserved | Disclaimer/Privacy