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Porphyromonas gingivalis Search Results

Record: 1 of 1  
MiniMap IGR0136 IGR0133 IGR0134 IGR0132 IGR0137 IGR0135 IGR0131 noxA,noxC, - PG0160 Pg-II fim c, - PG0161 PG0164 PG0166 ISPg4, - PG0162 PG0165 mfa1, - PG0163 PG0167 noxA,noxC, - PG0160 Pg-II fim c, - PG0161 PG0164 PG0166 ISPg4, - PG0162 PG0165 mfa1, - PG0163 PG0167 Type: IS element, Name: ISPg4 - 7 noxA,noxC, - PG0160 Pg-II fim c, - PG0161 PG0164 PG0166 ISPg4, - PG0162 PG0165 mfa1, - PG0163 PG0167


LANL Gene ID: PG0163

GenBank Locus Tag: PG0178

DNA Molecule Name:
1  

Genomic Island ID:
4

GenBank ID:


 Gene Name:
mfa1  

 Definition:
Mfa1 protein, 67 kDa fimbrillin

 Cellular Location:
Periplasm, Extracellular [Evidence]

 Gene Start:
200458

Gene Stop:
201840

Gene Length:
1383

Molecular Weight*:
50074

pI*:
6.70

Net Charge*:
-1.34

EC:
 

 Functional Class:
Cell envelope; Surface structures  

 Gene Ontology:

Pathway: pathway table

 Primary Evidence:
See Fimbrillins



Park Y, Simionato MR, Sekiya K, Murakami Y, James D, Chen W, Hackett M, Yoshimura F, Demuth DR, Lamont RJ.
The short fimbriae of Porphyromonas gingivalis and their role in coadhesion with Streptococcus gordonii.
In press

Oshikawa M, Sugano N, Koshi R, Ikeda K, Ito K.
Differential gene induction in macrophage-like human cells by two types of Porphyromonas gingivalis: a microarray study.
J Oral Sci. 2004 Mar;46(1):9-14.
PMID: 15141718

Chung WO, Demuth DR, Lamont RJ.
Identification of a Porphyromonas gingivalis receptor for the Streptococcus gordonii SspB protein.
Infect Immun. 2000 Dec;68(12):6758-62.
PMID: 11083792

Hongyo H, Kokeguchi S, Kurihara H, Miyamoto M, Maeda H, Takashiba S, Murayama Y.
Comparative study of two outer membrane protein genes from Porphyromonas gingivalis.
Microbios. 1998;95(381):91-100.
PMID: 9871998

Hongyo H, Kurihara H, Kokeguchi S, Miyamoto M, Maeda H, Hayakawa M, Abiko Y, Takashiba S, Murayama Y.
Molecular cloning and characterization of the gene encoding 53 kD outer membrane protein of Porphyromonas gingivalis.
Microbios. 1997;92(370):47-57.
PMID: 9569663

Hamada N, Sojar HT, Cho MI, Genco RJ.
Isolation and characterization of a minor fimbria from Porphyromonas gingivalis.
Infect Immun. 1996 Nov;64(11):4788-94.
PMID: 8890240

Ogawa T, Yasuda K, Yamada K, Mori H, Ochiai K, Hasegawa M.
Immunochemical characterisation and epitope mapping of a novel fimbrial protein (Pg-II fimbria) of Porphyromonas gingivalis.
FEMS Immunol Med Microbiol. 1995 Jun;11(3):247-55.
PMID: 7581276

Kokeguchi S, Miyamoto M, Ohyama H, Hongyo H, Takigawa M, Kurihara H, Murayama Y, Kato K.
Biochemical properties of the major outer membrane proteins of Porphyromonas gingivalis.
Microbios. 1994;77(313):247-52.
PMID: 8208139

 Comment:
The following comment was kindly provided by Richard J. Lamont, Professor, University of Florida.

PG0163 is clearly the Hamada minor fimA. Chung et al. (2000, and note correction in Infection and Immunity, 2001, 69 (12) 7964) provide evidence that PG0163 binds to the SspB protein of S.gordonii.


TIGR ID: PG0178

 Proteomic Data: Proteomic Data Search
TIGR Annotationcell surface protein, interruption, GroupC (cell envelope)
ORF #PG-PP/PG-PPC1PG-PP/PG-PPC2
Spectral CountPeptide IntensitySpectral CountPeptide Intensity
ProqValProqValProqValProqVal
TIGRPG01780.210.018-0.570.0340.130.054-0.570.034
LANLPG01631.160.681.090.98
ConsensusSP1IP1SP2IP2

Human Oral Microbiome Database:
View in HOMD Genome Viewer

 Blast Summary:  PSI-Blast Search
This sequence corresponds to 22255314 in Genbank.


 Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|3345479|dbj|BAA31954.1|  67kDa fimbrillin [Porphyromonas ...   810   0.0  
 gi|523232|dbj|BAA05959.1|  cell surface protein precursor [P...   808   0.0  
 gi|523234|dbj|BAA05960.1|  cell surface protein precursor [P...   808   0.0  
 gi|2541865|dbj|BAA22842.1|  pga67 [Porphyromonas gingivalis]      806   0.0  
 gi|22255319|dbj|BAC07530.1|  Pg-II fimbriae b [Porphyromonas...   728   0.0  
 gi|47826535|dbj|BAD20817.1|  Pg-II fimbriae c [Porphyromonas...   719   0.0  
 gi|22255316|dbj|BAC07529.1|  Pg-II fimbriae a [Porphyromonas...   474   e-132
 gi|5832527|dbj|BAA84008.1|  53kDa major outer membrane prote...   128   9e-28


InterPro Summary:  InterProScan

No hits reported.

COGS Summary:  COGS Search
No hit to the COGs database.
Blocks Summary:  Blocks Search
No significant hit to the Blocks database.

 ProDom Summary:  Protein Domain Search
No significant hit to the ProDom database.

Paralogs:  Local Blast Search
No paralogs found in P. gingivalis.

Pfam Summary:  Pfam Search
No significant hits to the Pfam 11.0 database

 Structural Feature(s):
Feature Type  Start  Stop
non-globular  
1  
190
non-globular  
400  
461

Top PDB Hits:
No significant hits to the PDB database (E-value < E-10).

Gene Protein Sequence:
MPQEETFRTLMILKPKKGIKVNSAVGKTVKVYVVLNDIAGKAKALLANVN
AADFDAKFKEVIELSTQAQALGTVADGPNPATAAGKIAKKNGTTDETIMM
TCLQPSDALTIEAAVSEANAIAGIKNQAKVTVERSVARAMVSTKAQSYEI
KATTQIGSIAAGDVLATITDIRWVVAQGERRQYLSKKRGTVPENTWVTPG
SGFVPTSSTFHTNATEYYDYAGLWEDHNTNEAVISGTQVPTLADYQLQDV
TGELANALSGKFLLPNTHKSGANAASSDYKRGNTAYVLVRAKFTPKKEAF
IDRGKTYSDNTAVPEYVAGEDFFVGENGQFYVSMKSVTDPKVGGVAGMKA
HKYVKGKVLYYAWLNPSTTSPDSWWNSPVVRNNIYHIHIKSIKKLGFNWN
PLVPDPDPNNPENPNNPDPNPDEPGTPVPTDPENPLPDQDTFMSVEVTVL
PWKVHSYEVDL

Gene Nucleotide Sequence:  Sequence Viewer
ATGCCTCAAGAAGAAACTTTTAGGACACTAATGATTTTGAAACCCAAAAA
AGGCATCAAGGTTAATTCTGCAGTCGGCAAGACGGTTAAAGTATATGTGG
TGCTCAATGACATCGCAGGCAAGGCAAAAGCCCTTTTGGCAAATGTTAAT
GCAGCAGACTTTGATGCTAAATTCAAAGAGGTAATCGAACTGTCTACTCA
GGCTCAAGCTTTAGGTACGGTAGCCGATGGCCCAAATCCTGCTACGGCGG
CTGGAAAGATTGCCAAAAAGAATGGTACTACTGATGAGACAATCATGATG
ACCTGTTTGCAGCCTTCTGATGCTTTGACTATCGAAGCTGCTGTATCCGA
GGCCAATGCTATCGCAGGGATTAAGAATCAGGCCAAGGTTACGGTGGAGC
GTTCTGTAGCACGTGCGATGGTTTCAACGAAAGCCCAGAGCTATGAAATT
AAAGCTACTACTCAAATTGGTAGTATTGCTGCTGGTGATGTTTTGGCTAC
CATTACGGATATCAGATGGGTTGTTGCTCAAGGAGAACGTCGCCAATACC
TAAGCAAGAAAAGAGGAACTGTTCCAGAAAATACTTGGGTTACTCCGGGC
TCTGGTTTCGTTCCTACTAGCAGCACTTTCCATACAAATGCTACCGAGTA
TTATGATTATGCCGGTCTGTGGGAAGATCATAATACAAATGAGGCCGTAA
TCAGTGGAACTCAAGTGCCGACTTTGGCTGATTATCAGCTCCAGGACGTG
ACTGGCGAATTGGCAAATGCCCTTTCAGGGAAATTCCTGCTGCCTAATAC
CCATAAGTCAGGTGCTAATGCTGCTTCGTCAGACTATAAGAGAGGTAATA
CTGCCTATGTATTGGTTCGTGCGAAGTTTACTCCCAAGAAAGAAGCCTTT
ATCGATAGAGGTAAAACTTATTCAGATAATACTGCAGTTCCTGAATATGT
AGCAGGTGAAGATTTCTTCGTTGGTGAGAATGGCCAGTTCTATGTGTCTA
TGAAATCCGTTACAGACCCCAAGGTAGGTGGTGTAGCTGGTATGAAGGCA
CACAAATATGTGAAAGGCAAAGTACTGTACTATGCTTGGTTGAATCCCAG
TACTACTTCTCCCGATTCATGGTGGAATTCTCCCGTTGTGCGCAACAATA
TCTACCATATCCACATCAAGAGCATCAAGAAGTTGGGCTTCAACTGGAAT
CCTTTGGTGCCGGATCCGGATCCTAACAATCCGGAAAATCCGAATAACCC
TGACCCGAATCCGGATGAGCCGGGTACTCCTGTTCCTACAGATCCGGAGA
ACCCCTTACCTGATCAGGATACGTTCATGTCGGTTGAGGTTACAGTTTTG
CCTTGGAAAGTTCATTCCTATGAGGTTGATCTC

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