Basic Search | Intermediate Search | Advanced Search | Gene Image Map |  Sequence Search |  Protein Motif Search |  Repeat Search |  DNA/RNA Motif Search |  Home

Porphyromonas gingivalis Search Results

Record: 1 of 1  
MiniMap IGR0179 IGR0178 IGR0174 IGR0180 IGR0175 IGR0182 IGR0177 IGR0181 IGR0176 PG0217 PG0213 PG0218 PG0219 PG0212 PG0212.1 ung, - PG0216 PG0215 ctpA, - PG0214 PG0217 PG0213 PG0218 PG0219 PG0212 PG0212.1 ung, - PG0216 PG0215 ctpA, - PG0214 PG0217 PG0213 PG0219 PG0212 PG0218 PG0212.1 ung, - PG0216 PG0215 ctpA, - PG0214


LANL Gene ID: PG0214

GenBank Locus Tag: PG0235

DNA Molecule Name:
1  

GenBank ID:
34540086

Gene Name:
ctpA  

Definition:
carboxyl-terminal protease

Cellular Location:
Cytoplasm, Periplasm, Extracellular [Evidence]

Gene Start:
271769

Gene Stop:
273289

Gene Length:
1521

Molecular Weight*:
57128

pI*:
9.50

Net Charge*:
6.64

EC:
3.4.21.102  

Functional Class:
Protein fate; Degradation of proteins, peptides and glycopeptides  

Gene Ontology:
Biological process
  GO:0006508    proteolysis

Molecular function
  GO:0005515    protein binding
  GO:0008236    serine-type peptidase activity


Pathway: pathway table

Comment:
No significant hits in gapped BLAST to the C-terminal ~150 amino acids of this protein. Possible stop coordinate error?

TIGR ID: PG0235

Proteomic Data: Proteomic Data Search
TIGR Annotationcarboxyl-terminal protease, GroupM (protein fate)
ORF #PG-PP/PG-PPC1PG-PP/PG-PPC2
Spectral CountPeptide IntensitySpectral CountPeptide Intensity
ProqValProqValProqValProqVal
TIGRPG0235-0.140.36
LANLPG02140.910.14
ConsensusSP1IP1SP2IP2

Human Oral Microbiome Database:
View in HOMD Genome Viewer

 Blast Summary:  PSI-Blast Search
Numerous significant hits to carboxy-terminal protease proteins in gapped BLAST; e.g. residues 3-319 are 41% similar to gbAAF85501.1AE004076_6 carboxyl-terminal protease of Xylella fastidiosa, residues 19-319 are 39% similar to gbAAD04178.1 carboxy-terminal protease of Bartonella quintana, residues 2-318 are 35% similar to dbjBAB07318.1 carboxy-terminal processing protease of Bacillus halodurans.

This sequence is similar to BT3035.

 Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|34540086|ref|NP_904565.1|  carboxyl-terminal protease [Po...  1023   0.0  
 gi|154490320|ref|ZP_02030581.1|  hypothetical protein PARMER...   524   e-147
 gi|150009932|ref|YP_001304675.1|  carboxy-terminal processin...   517   e-145
 gi|156859091|gb|EDO52522.1|  hypothetical protein BACUNI_041...   493   e-137
 gi|156109689|gb|EDO11434.1|  hypothetical protein BACOVA_026...   487   e-136
 gi|153807003|ref|ZP_01959671.1|  hypothetical protein BACCAC...   483   e-134
 gi|60683747|ref|YP_213891.1|  putative carboxy-terminal proc...   479   e-133
 gi|53715826|ref|YP_101818.1|  carboxy-terminal processing pr...   479   e-133
 gi|29348444|ref|NP_811947.1|  carboxy-terminal processing pr...   479   e-133
 gi|150003805|ref|YP_001298549.1|  carboxy-terminal processin...   476   e-132


InterPro Summary:  InterProScan

InterPro
IPR001478
Domain
PDZ/DHR/GLGF
PF00595 [53-134]T 5.49999942632762E-4 PF00595 PDZ PDZ
SM00228 [64-137]T 6.400000000000191E-14 SM00228 PDZ PDZ
PS50106 [53-137]T 0.0 PS50106 PDZ PDZ
SSF50156 [60-150]T 3.4E-17 SSF50156 PDZ PDZ
InterPro
IPR004447
Family
Peptidase S41A, C-terminal protease
TIGR00225 [16-350]T 2.2635401027597006E-74 TIGR00225 prc prc
InterPro
IPR005151
Domain
Peptidase S41
PF03572 [163-329]T 4.79998722798104E-62 PF03572 Peptidase_S41 Peptidase_S41
SM00245 [137-321]T 1.7000000000000995E-48 SM00245 TSPc TSPc
noIPR
unintegrated
unintegrated
G3DSA:2.30.42.10 [49-137]T 2.59999946718996E-7 G3DSA:2.30.42.10 G3DSA:2.30.42.10 G3DSA:2.30.42.10
G3DSA:3.90.226.10 [140-320]T 6.89998448199267E-45 G3DSA:3.90.226.10 G3DSA:3.90.226.10 G3DSA:3.90.226.10
PTHR22939 [77-261]T 4.39999967439742E-7 PTHR22939 PTHR22939 PTHR22939
PTHR22939:SF10 [77-261]T 4.39999967439742E-7 PTHR22939:SF10 PTHR22939:SF10 PTHR22939:SF10
SSF52096 [1-387]T 3.9000000000000003E-69 SSF52096 SSF52096 SSF52096


COGS Summary:  COGS Search
BeTs to 10 clades of COG0793
COG name: Periplasmic protease
Functional Class: M
The phylogenetic pattern of COG0793 is -----qvCeB-huj--olinx
Number of proteins in this genome belonging to this COG is 4
Blocks Summary:  Blocks Search
No significant hit to the Blocks database.

 ProDom Summary:  Protein Domain Search
Residues 163-318 are 40% similar to a (PROTEASE CARBOXYL-TERMINAL PRECURSOR) protein domain (PD004132 which is seen in O30968_NOSPU.


Paralogs:  Local Blast Search
Residues 8-497 are 40% similar to PG1617, a predicted carboxyl-terminal proteinase. Similarites are also seen to PG0942, a probable tail-specific protease.

Pfam Summary:  Pfam Search
Residues 53 to 134 (E-value = 7.8e-06) place PG0214 in the PDZ family which is described as PDZ domain (Also known as DHR or GLGF) (PF00595)
Residues 161 to 324 (E-value = 2.9e-67) place PG0214 in the Peptidase_S41 family which is described as Peptidase family S41B (PF03572)

 Structural Feature(s):
Feature Type  Start  Stop
No predicted structural features.  
  

Top PDB Hits:
-47% similar to PDB:1FC6 PHOTOSYSTEM II D1 C-TERMINAL PROCESSING PROTEASE (E_value = 8.0E_29);
-47% similar to PDB:1FC7 PHOTOSYSTEM II D1 C-TERMINAL PROCESSING PROTEASE (E_value = 8.0E_29);
-47% similar to PDB:1FC9 PHOTOSYSTEM II D1 C-TERMINAL PROCESSING PROTEASE (E_value = 8.0E_29);
-47% similar to PDB:1FCF PHOTOSYSTEM II D1 C-TERMINAL PROCESSING PROTEASE (E_value = 8.0E_29);

Gene Protein Sequence:
MKEALRKLETAVYAISSLYVDSVDNNKLTEYAIRGVLSELDPHSVYSDAE
ETKSELEPLNAGFDGIGVQFNMLTDTVYVVQVIAGGPSEKAGLLAGDRIV
SVDDTVIAGIKMKTNDVMKRLRGPRGSKVKLGVWRGNDRLNITVKRGLVP
VHSREACYMVDERTGYIRLSRFSRTTYDEFAEGIALLRGRGMQQLVLDLR
FNGGGILDQAVEMAGTFLPEGSTVLTVRNNRMPRISERMEATSNNLLPKD
LPLVVLVNEFSASASEILAGAIQDWDRGVVIGRRTFGKGLVQRPLPFQDG
SMIRLTIARYYTPSGRSIQKPYAKGNFKAYEQELIGRFKHGESIHSDSIR
FPDSLRYKTLVTGRTVYGGGGIMPDLFIPTDTALFNKLHRELLNKGIFNR
AVLKYVDAHRQKLRQRFPDRQSYATFSIPEELTESLKAFAEAEKITWSTE
LFAQAEELIKCQLHAYIARDILGENDFFYFFNRMDKEYIKALDLLNDPDE
YKRLLGK

Gene Nucleotide Sequence:  Sequence Viewer
ATGAAAGAGGCCCTACGTAAGCTGGAAACGGCTGTGTATGCTATCAGCAG
CCTGTATGTGGACAGTGTGGACAACAACAAGCTGACCGAATATGCCATTC
GAGGGGTCTTGAGCGAATTGGACCCTCACTCTGTTTATTCCGATGCAGAG
GAGACAAAGAGCGAATTGGAGCCTCTAAATGCCGGATTCGACGGTATAGG
CGTGCAGTTCAATATGCTCACGGATACGGTCTATGTGGTACAGGTGATTG
CCGGAGGCCCTTCGGAAAAGGCCGGATTGTTGGCCGGTGATCGCATTGTA
TCAGTGGATGATACTGTCATTGCAGGAATCAAGATGAAGACCAATGACGT
GATGAAACGCTTGCGTGGTCCGCGAGGAAGCAAGGTCAAACTCGGCGTAT
GGCGGGGGAACGACAGACTCAATATCACCGTCAAGCGAGGCCTTGTCCCT
GTTCATAGCCGCGAGGCCTGCTATATGGTCGACGAACGTACAGGGTATAT
CAGACTGAGTAGATTTTCGCGCACTACCTACGATGAGTTTGCCGAGGGCA
TAGCTCTTTTGCGAGGACGTGGTATGCAGCAGTTGGTGCTTGATCTGAGA
TTCAATGGTGGCGGTATACTTGATCAGGCTGTGGAGATGGCCGGAACTTT
TCTACCCGAAGGAAGTACGGTACTGACCGTCAGAAACAATCGTATGCCAC
GGATCAGTGAGCGCATGGAGGCTACGAGCAATAACCTCCTCCCGAAGGAC
TTGCCTTTGGTCGTTCTCGTCAATGAGTTTTCGGCTTCAGCCAGCGAGAT
ATTGGCCGGGGCCATACAAGATTGGGACAGAGGAGTCGTTATCGGACGGC
GTACTTTCGGCAAAGGACTGGTACAGCGTCCATTGCCCTTTCAGGATGGT
TCGATGATCCGGCTGACTATCGCCCGCTATTATACGCCTTCGGGACGTAG
CATCCAGAAACCTTATGCAAAAGGGAATTTCAAAGCATACGAACAGGAAT
TGATCGGTCGCTTCAAACACGGCGAATCCATCCACAGCGACAGCATCCGT
TTCCCCGATTCTCTTCGCTACAAGACTCTCGTCACGGGGCGCACCGTTTA
TGGTGGGGGAGGCATTATGCCGGATCTTTTCATCCCAACGGATACGGCCT
TGTTCAACAAGCTGCATCGCGAGCTGCTGAACAAGGGTATCTTTAATCGG
GCTGTACTCAAATATGTGGATGCACATCGTCAGAAGCTGCGCCAACGCTT
CCCCGACAGACAGTCATACGCCACGTTTAGCATTCCCGAAGAACTGACTG
AAAGCCTGAAAGCATTTGCCGAAGCTGAGAAAATCACATGGAGCACCGAA
CTTTTTGCTCAAGCCGAAGAGCTTATCAAGTGTCAGCTCCATGCCTATAT
CGCACGTGATATTCTGGGGGAGAACGACTTCTTCTATTTCTTCAATCGCA
TGGATAAGGAATATATAAAAGCACTCGATCTCCTCAATGATCCCGACGAA
TACAAACGTCTCCTCGGAAAG

Los Alamos National Laboratory • Est 1943

Operated by Los Alamos National Security, LLC for the U.S. Department of Energy's National Nuclear Security Administration
Inside | © Copyright 2006 LANS LLC All rights reserved | Disclaimer/Privacy