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Porphyromonas gingivalis Search Results

Record: 1 of 1  
MiniMap IGR0350 IGR0351 IGR0353 IGR0348 IGR0352 IGR0349 IGR0347 PG0415.1 ISPg5, - PG0419 ISPg5, - PG0418 ISPgX, - PG0421 PG0422 ISPg1, - PG0420 PG0415 PG0416 PG0415.1 ISPg5, - PG0419 ISPg5, - PG0418 ISPgX, - PG0421 PG0422 ISPg1, - PG0420 PG0415 PG0416 Type: IS element, Name: ISPg1 - 2 Type: IS element, Name: ISPg5 - 8 Type: IS element, Name: ISPg5 - 8 PG0415.1 ISPg5, - PG0419 ISPg5, - PG0418 ISPgX, - PG0421 PG0422 ISPg1, - PG0420 PG0415 PG0416 PG0417 PG0417


LANL Gene ID: PG0418

GenBank Locus Tag: PG0458

DNA Molecule Name:
1  

Genomic Island ID:
22

GenBank ID:
34540277

 Gene Name:
ISPg5  

 Definition:
ISPg5 transposase

 Cellular Location:
Cytoplasm [Evidence]

 Gene Start:
501554

Gene Stop:
500619

Gene Length:
936

Molecular Weight*:
36305

pI*:
9.90

Net Charge*:
13.52

EC:
 

 Functional Class:
Transposon functions  

 Gene Ontology:
Biological process
  GO:0015074    DNA integration

Molecular function
  GO:0003677    DNA binding


 Pathway: pathway table

 Primary Evidence:
Califano,J.V., Kitten,T., Lewis,J.P., Macrina,F.L., Fleischmann,R.D., Fraser,C.M.,Duncan,M.J. and Dewhirst,F.E. Characterization of Porphyromonas gingivalis insertion
sequence-like element ISPg5.
Infect. Immun. 68 (9), 5247-5253 (2000)

 Comment:
One of eleven ISPg5 elements in the genome (see Paralogs). Califano et al. report considerable strain diversity of these (Infect. Immun. 68 (9), 5247-5253 (2000)).

Member of the IS3 family of insertion elements. See PG0419 for associated ORF.

TIGR ID: PG0458

 Human Oral Microbiome Database:
View in HOMD Genome Viewer

 Blast Summary:  PSI-Blast Search
PG0418 is equivalent to the previously reported gb|AAF69128.1| in GenBANK.

Numerous significant hits in gapped BLAST to transposase proteins; e.g. residues 91-213 are 56% similar to transposase homolog (U67062) of Bacteriodes thetaiotaomicrom, residues 64-287 are 32% similar to InsB (AF153317) of Shigella dysenteriae, residues 64-268 are 33% similar to Hp1 (AF081284) of E.coli.

 Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|34540277|ref|NP_904756.1|  ISPg5, transposase Orf2 [Porph...   630   e-179
 gi|34539915|ref|NP_904394.1|  ISPg5 transposase Orf2 [Porphy...   627   e-178
 gi|34540399|ref|NP_904878.1|  ISPg5, transposase Orf2 [Porph...   620   e-176
 gi|118200270|dbj|BAF37077.1|  transposase Orf2 [Porphyromona...   620   e-176
 gi|34541341|ref|NP_905820.1|  ISPg5, transposase Orf2 [Porph...   619   e-176
 gi|34540248|ref|NP_904727.1|  ISPg5, transposase Orf2 [Porph...   618   e-175
 gi|34541287|ref|NP_905766.1|  ISPg5, transposase Orf2 [Porph...   616   e-175
 gi|34539888|ref|NP_904367.1|  ISPg5 transposase Orf2 [Porphy...   615   e-174
 gi|34540696|ref|NP_905175.1|  ISPg5, transposase Orf2 [Porph...   615   e-174
 gi|34541641|ref|NP_906120.1|  ISPg5, transposase Orf2 [Porph...   614   e-174


InterPro Summary:  InterProScan

InterPro
IPR001584
Domain
Integrase, catalytic core
PF00665 [110-273]T 6.2e-31 PF00665 rve rve
PS50994 [110-276]T 18.309 PS50994 INTEGRASE INTEGRASE
noIPR
unintegrated
unintegrated
G3DSA:3.30.420.10 [113-281]T 2.9e-06 G3DSA:3.30.420.10 no description no description


COGS Summary:  COGS Search
No hit to the COGs database.
Blocks Summary:  Blocks Search
***** PF01836 (Transposase) with a combined E-value of 4.3e-23.
    PF01836B    103-154
    PF01836C    181-190
    PF01836D    215-222
    PF01836E    253-272


 ProDom Summary:  Protein Domain Search
No significant hit to the ProDom database.

Paralogs:  Local Blast Search
PG0418 is paralogously related to PG1861, PG1491, PG0391, PG0007, PG1436, PG1796, PG0034, PG0533, PG1247 and PG0841.

Pfam Summary:  Pfam Search
Residues 110 to 273 (E-value = 6.6e-31) place PG0418 in the rve family which is described as Integrase core domain (PF00665)

 Structural Feature(s):
Feature Type  Start  Stop
No predicted structural features.  
  

Top PDB Hits:
No significant hits to the PDB database (E-value < E-10).

Gene Protein Sequence:
LLGFSRQAFYKRHLNDLARHEEDVLCSSIIQYCWHLRQAEHLPQAGFREL
MVLCQQYFGPKFTLGRDRFCALLRRHGMMLRKRSVRPRTTNSRHRLYKYE
DLLNTEPKFVPQRPGELLVADITYVAYQDGFAYLSLLTDAYSRCIVGYCL
HPTLEVEGCLNALHQAFAFYDQHQIDTSNMIHHSDRGIQYAGKSYTDLLH
GRGWRISMTQTGDPLHNALAERMNNTLKNSWHISSSKQSFDQALLSVEQA
VRMYNEARPHQALGAKTPMQVITPESENPLLTRREHGPEIAPELYRRMNV
RQRANFARVNRN

Gene Nucleotide Sequence:  Sequence Viewer
CTGCTTGGCTTCAGCCGTCAGGCCTTTTATAAACGTCATCTCAACGATTT
AGCTAGGCATGAGGAGGATGTCCTATGCAGTAGTATCATCCAATATTGTT
GGCACTTAAGACAAGCAGAGCACCTACCTCAAGCCGGCTTCCGAGAGCTC
ATGGTGCTTTGTCAGCAATACTTCGGCCCCAAGTTCACGCTTGGGCGCGA
TCGCTTTTGCGCCCTACTCAGACGCCATGGTATGATGCTGCGCAAACGGT
CTGTGCGCCCTCGGACAACCAACTCTCGGCATAGGCTCTACAAGTATGAA
GACCTGCTCAATACAGAGCCTAAGTTTGTGCCTCAAAGACCTGGGGAACT
CCTTGTAGCAGACATCACCTACGTGGCTTACCAAGATGGGTTTGCCTATC
TCTCCCTACTGACCGATGCCTATAGTCGCTGTATCGTAGGGTATTGCTTA
CATCCTACCCTAGAGGTTGAAGGCTGTTTGAATGCTCTACATCAAGCCTT
TGCTTTCTACGATCAGCATCAAATTGATACGAGCAATATGATTCATCATA
GCGACCGAGGCATTCAGTATGCCGGTAAGAGCTACACCGATCTGTTGCAT
GGGCGAGGCTGGCGCATCAGCATGACTCAGACGGGAGATCCTCTGCATAA
TGCATTGGCTGAGCGGATGAACAATACGCTCAAGAACTCGTGGCACATCT
CCTCTTCGAAGCAGTCTTTTGATCAAGCACTCCTTTCTGTAGAACAAGCC
GTGCGCATGTACAACGAGGCGCGTCCACATCAAGCTCTAGGGGCGAAAAC
GCCTATGCAAGTCATTACACCGGAGTCTGAAAATCCGTTACTAACGAGGA
GGGAGCATGGGCCAGAGATTGCCCCCGAGCTATACCGAAGGATGAATGTC
AGACAAAGAGCTAACTTTGCTCGTGTCAACCGAAAT

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