Basic Search | Intermediate Search | Advanced Search | Gene Image Map |  Sequence Search |  Protein Motif Search |  Repeat Search |  DNA/RNA Motif Search |  Home

Porphyromonas gingivalis Search Results

Record: 1 of 1  
MiniMap IGR0777 IGR0776 IGR0775 IGR0779 IGR0781 IGR0778 PG0915.1 PG0912 pabB, - PG0913 PG0914 PG0911 PG0916 PG0910 PG0915.1 PG0912 pabB, - PG0913 PG0914 PG0911 PG0916 PG0910 PG0915.1 PG0912 pabB, - PG0913 PG0914 PG0911 PG0916 PG0910 PG0915 PG0915


LANL Gene ID: PG0913

GenBank Locus Tag:

DNA Molecule Name:
1  

GenBank ID:


Gene Name:
pabB  

Definition:
possible para-aminobenzoate synthase component I

Cellular Location:
Cytoplasm [Evidence]

Gene Start:
1086822

Gene Stop:
1085812

Gene Length:
1011

Molecular Weight*:
38035

pI*:
6.20

Net Charge*:
-3.47

EC:
 

Functional Class:
Biosynthesis of cofactors, prosthetic groups and carriers; Folic acid  

Gene Ontology:
Biological process
  GO:0009058    biosynthetic process


Pathway: pathway table

Comment:
NO TIGR ID corresponds to this gene.

Human Oral Microbiome Database:
View in HOMD Genome Viewer

Blast Summary:  PSI-Blast Search
Numerous significant hits in gapped BLAST; e.g. residues 12-336 are 45% similar to gb|AAC22834.1| H. influenzae predicted coding region HI1170 of Haemophilus influenzae Rd, residues 82-328 are 33% similar to gb|AAF42299.1| para-aminobenzoate synthetase component I/4-amino-4-deoxychorismate lyase, putative of Neisseria meningitidis MC58, residues 112-333 are 33% similar to gb|AAB89646.1| anthranilate synthase component I (trpE) of Archaeoglobus fulgidus.

Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|29346177|ref|NP_809680.1|  para-aminobenzoate synthase co...   317   5e-85
 gi|124006609|ref|ZP_01691441.1|  TrpE protein [Microscilla m...   308   3e-82
 gi|153806410|ref|ZP_01959078.1|  hypothetical protein BACCAC...   308   3e-82
 gi|60681813|ref|YP_211957.1|  para-aminobenzoate synthase co...   307   8e-82
 gi|53713528|ref|YP_099520.1|  para-aminobenzoate synthase co...   306   1e-81
 gi|150007816|ref|YP_001302559.1|  putative para-aminobenzoat...   304   4e-81
 gi|156859498|gb|EDO52929.1|  hypothetical protein BACUNI_037...   301   3e-80
 gi|156110253|gb|EDO11998.1|  hypothetical protein BACOVA_024...   299   1e-79
 gi|150004771|ref|YP_001299515.1|  putative para-aminobenzoat...   297   5e-79
 gi|152990124|ref|YP_001355846.1|  anthranilate/para-aminoben...   296   1e-78


InterPro Summary:  InterProScan

InterPro
IPR005801
Domain
Anthranilate synthase component I and chorismate binding protein
PD000779 [111-328]T 5e-64 PD000779 Q8A9P8_BACTN_Q8A9P8; Q8A9P8_BACTN_Q8A9P8;
PR00095 [176-189]T 4.4e-11 PR00095 ANTSNTHASEI[190-203]T 4.4e-11 PR00095 ANTSNTHASEI[274-288]T 4.4e-11 PR00095 ANTSNTHASEI[288-302]T 4.4e-11 PR00095 ANTSNTHASEI ANTSNTHASEI
PF00425 [86-335]T 1.5e-18 PF00425 Chorismate_bind Chorismate_bind
noIPR
unintegrated
unintegrated
G3DSA:3.60.120.10 [75-336]T 2.1e-58 G3DSA:3.60.120.10 no description no description
PTHR11236 [86-333]T 2e-101 PTHR11236 AMINOBENZOATE/ANTHRANILATE SYNTHASE AMINOBENZOATE/ANTHRANILATE SYNTHASE
PTHR11236:SF4 [86-333]T 2e-101 PTHR11236:SF4 gb def: Putative para-aminobenzoate synthase component I gb def: Putative para-aminobenzoate synthase component I


COGS Summary:  COGS Search
BeTs to 11 clades of COG0147
COG name: Anthranilate/para-aminobenzoate synthases component II
Functional Class: E,H
The phylogenetic pattern of COG0147 is amt-YQvCEBRHUJ-------
Number of proteins in this genome belonging to this COG is 1
Blocks Summary:  Blocks Search
***** PR00095 (Anthranilate synthase component I signature) with a combined E-value of 1.5e-13.
    PR00095A    176-189
    PR00095B    190-203
    PR00095C    274-288


 ProDom Summary:  Protein Domain Search
Residues 90-332 are 51% similar to a (SYNTHASE ANTHRANILATE BIOSYNTHESIS LYASE COMPONENT I) protein domain (PD000779 which is seen in Q57527_HAEIN.


Paralogs:  Local Blast Search
Residues 45-332 are 25% similar to PG1334, a predicted
isochorismate synthase protein.

Pfam Summary:  Pfam Search
Residues 86 to 335 (E-value = 2.8e-19) place PG0913 in the Chorismate_bind family which is described as chorismate binding enzyme (PF00425)

 Structural Feature(s):
Feature Type  Start  Stop
non-globular  
230  
277

Top PDB Hits:
-48% similar to PDB:1K0E THE CRYSTAL STRUCTURE OF AMINODEOXYCHORISMATE SYNTHASE FROM FORMATE GROWN CRYSTALS (E_value = 1.1E_20);
-48% similar to PDB:1K0G THE CRYSTAL STRUCTURE OF AMINODEOXYCHORISMATE SYNTHASE FROM PHOSPHATE GROWN CRYSTALS (E_value = 1.1E_20);
-49% similar to PDB:1I7Q ANTHRANILATE SYNTHASE FROM S. MARCESCENS (E_value = 2.9E_13);
-49% similar to PDB:1I7S ANTHRANILATE SYNTHASE FROM SERRATIA MARCESCENS IN COMPLEX WITH ITS END PRODUCT INHIBITOR L-TRYPTOPHAN (E_value = 2.9E_13);
-48% similar to PDB:1QDL THE CRYSTAL STRUCTURE OF ANTHRANILATE SYNTHASE FROM SULFOLOBUS SOLFATARICUS (E_value = 4.1E_12);

Gene Protein Sequence:
MTKAYGAGCPFQMKAEETIRRMDESGRCGRSFLFAIDFEMDEGIFISEPL
NQKEILFDVRGQGNAPTATDTNESKAPVTFIPHPESLETYRHRFDRIRTA
LMRGDSFLANLTIATPIEMNISLEEVFSRSRASYKLLIPGRLVCFSPERF
VKIENGQISTNPMKGTIDASLPDAAGRLLSDYKETAEHRTIVDLLRNDLN
RVSHHVRVSRFRYLDELHTNKGRLLQMSSEITGTLPAEKEKRFGSIIQEL
LPAGSISGAPKEATIEAIREAEGQQRGFYTGVFGYFDGSSFDSAVMIRYI
EQLPDGHYLFRSGGGITINSRCDDEYRETQQKVYLPF

Gene Nucleotide Sequence:  Sequence Viewer
ATGACAAAGGCTTACGGGGCTGGCTGCCCCTTTCAAATGAAGGCAGAGGA
AACGATCAGGCGAATGGATGAATCCGGCCGGTGCGGACGATCATTTCTGT
TTGCCATAGACTTTGAGATGGATGAGGGGATCTTCATATCGGAACCGCTG
AATCAAAAAGAAATCCTATTCGACGTACGAGGACAAGGGAATGCACCCAC
AGCTACCGATACGAATGAGAGCAAGGCTCCCGTGACTTTTATCCCCCACC
CCGAATCATTGGAGACCTATCGACATCGTTTCGATCGGATCCGCACAGCC
CTGATGCGTGGCGATAGCTTCTTGGCCAATCTCACCATTGCTACGCCCAT
TGAGATGAATATCTCGCTTGAGGAGGTATTCAGTCGCAGTCGCGCCTCAT
ACAAGCTCTTGATTCCCGGACGACTGGTTTGTTTCAGTCCGGAACGATTT
GTCAAAATAGAGAATGGGCAAATTTCCACCAACCCGATGAAAGGGACCAT
AGATGCTTCCCTGCCGGATGCCGCCGGCCGTCTACTGTCCGACTATAAAG
AAACGGCCGAACATCGCACCATCGTAGATCTGTTACGCAACGACCTGAAC
CGAGTCAGTCACCACGTACGCGTCTCTCGCTTTCGCTATCTGGATGAACT
CCACACGAACAAGGGACGACTGCTGCAAATGAGTTCGGAGATCACAGGCA
CACTCCCTGCGGAAAAAGAAAAGCGTTTCGGCTCCATTATTCAAGAGCTA
CTACCCGCCGGCTCCATCAGCGGAGCACCCAAAGAGGCCACTATCGAAGC
TATACGGGAGGCAGAGGGGCAGCAACGAGGCTTCTACACAGGTGTTTTCG
GTTATTTCGACGGTAGCAGCTTCGATTCGGCTGTAATGATTCGCTACATC
GAACAGCTTCCCGATGGCCATTACCTTTTTCGCAGTGGCGGCGGCATTAC
CATCAACAGCCGCTGTGACGACGAATACCGCGAAACACAACAAAAGGTAT
ATCTGCCATTC

Los Alamos National Laboratory • Est 1943

Operated by Los Alamos National Security, LLC for the U.S. Department of Energy's National Nuclear Security Administration
Inside | © Copyright 2006 LANS LLC All rights reserved | Disclaimer/Privacy