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Porphyromonas gingivalis Search Results

Record: 1 of 1  
MiniMap IGR0777 IGR0783 IGR0779 IGR0782 IGR0781 IGR0778 PG0915.1 PG0912 pabB, - PG0913 ISPg1, - PG0918 ISPg3, - PG0919 PG0914 PG0917 PG0916 PG0915.1 PG0912 pabB, - PG0913 ISPg1, - PG0918 ISPg3, - PG0919 PG0914 PG0917 PG0916 Type: IS element, Name: ISPg1 - 2 Type: IS element, Name: ISPg3 fragment - 6 Type: IS element, Name: ISPg3 fragment - 6 PG0915.1 PG0912 pabB, - PG0913 ISPg1, - PG0918 ISPg3, - PG0919 PG0914 PG0917 PG0916 PG0915 PG0915


LANL Gene ID: PG0916

GenBank Locus Tag: PG1028

DNA Molecule Name:
1  

GenBank ID:
34540769

Gene Name:


Definition:
probable outer membrane lipoprotein P61

Cellular Location:
Periplasm [Evidence]

Gene Start:
1089461

Gene Stop:
1091155

Gene Length:
1695

Molecular Weight*:
62587

pI*:
5.00

Net Charge*:
-9.47

EC:
 

Functional Class:
Cell envelope  

Gene Ontology:
Molecular function
  GO:0005488    binding


Pathway: pathway table

Primary Evidence:
See Fimbrillins

Veith,P., Talbo,G., Slakeski,N., Dashper,S., Moore,C.,Paolini,R., Reynolds,E., Major outer membrane proteins and proteolytic processing of RgpA, and Kgp of Porphyromonas gingivalis W50, Biochem J. 2002 (in press).

Comment:
Veith et al. (2002) identified this protein by two-dimensional gel electrophoresis and peptide mass fingerprinting of outer membranes prepared from strain W50. This protein contains a putative lipoprotein signal sequence. The predicted start was at 1089812, but at Veith's suggestion the start coordinate was moved upstream 351 bp adding 117 aa to the N-terminus of this protein 2/27/2002.

* This change causes residue numbering in this annotation to shift. Add 117 for accuracy.

May be related to so called "secondary fimbrial proteins" such as PG1864, PG1893.

TIGR ID: PG1028

Proteomic Data: Proteomic Data Search
TIGR AnnotationTPR domain protein, GroupT (unknown function)
ORF #PG-PP/PG-PPC1PG-PP/PG-PPC2
Spectral CountPeptide IntensitySpectral CountPeptide Intensity
ProqValProqValProqValProqVal
TIGRPG10280.610.000150.040.24-0.451.7e-050.040.24
LANLPG09161.531.030.730.71
ConsensusSP1IP1SP2IP2

Human Oral Microbiome Database:
View in HOMD Genome Viewer

 Blast Summary:  PSI-Blast Search
PG0916 is 25% similar to a previously sequenced protein of P. gingivalis in Genbank AAD33939 and 26% similar to Genbank BAA33066.

Two weak hits in gapped BLAST; e.g. residues 260-375 are 31% similar to gb|AAG51433.1|AC008153_6 spindly (gibberellin signal transduction protein) of Arabidopsis thaliana, residues
256-359 are 28% similar to gb|AAF55179.1| CG5038 gene product of Drosophila melanogaster.

The 117 aa added to the N-terminus do not show similarity to any sequences in GenBank.


This sequence is similar to BT2844.

 Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|34540769|ref|NP_905248.1|  TPR domain protein [Porphyromo...   811   0.0  
 gi|150009359|ref|YP_001304102.1|  hypothetical protein BDI_2...   607   e-172
 gi|154490374|ref|ZP_02030635.1|  hypothetical protein PARMER...   606   e-171
 gi|153805792|ref|ZP_01958460.1|  hypothetical protein BACCAC...   548   e-154
 gi|156110489|gb|EDO12234.1|  hypothetical protein BACOVA_021...   544   e-153
 gi|50787940|emb|CAH05076.1|  putative plasminogen binding pr...   542   e-152
 gi|60683695|ref|YP_213839.1|  hypothetical protein BF4280 [B...   539   e-151
 gi|53715764|ref|YP_101756.1|  hypothetical protein BF4485 [B...   537   e-151
 gi|29348253|ref|NP_811756.1|  hypothetical protein BT_2844 [...   534   e-150
 gi|156859013|gb|EDO52444.1|  hypothetical protein BACUNI_040...   521   e-146


InterPro Summary:  InterProScan

InterPro
IPR001440
Repeat
Tetratricopeptide TPR_1
PF00515 [457-476]T 0.17 PF00515 TPR_1 TPR_1
InterPro
IPR011990
Domain
Tetratricopeptide-like helical
G3DSA:1.25.40.10 [374-540]T 9.9e-16 G3DSA:1.25.40.10 no description no description
InterPro
IPR013026
Domain
Tetratricopeptide region
SM00028 [388-421]T 0.035 SM00028 TPR[507-540]T 86 SM00028 TPR TPR
PS50005 [388-421]T 10.148 PS50005 TPR[451-484]T 6.815 PS50005 TPR[507-540]T 6.402 PS50005 TPR TPR
PS50293 [377-421]T 10.642 PS50293 TPR_REGION[421-454]T 6.768 PS50293 TPR_REGION TPR_REGION
InterPro
IPR013105
Repeat
Tetratricopeptide TPR_2
PF07719 [388-421]T 3.4e-05 PF07719 TPR_2 TPR_2
noIPR
unintegrated
unintegrated
PTHR23083 [374-470]T 2.4e-07 PTHR23083 TETRATRICOPEPTIDE REPEAT PROTEIN, TPR TETRATRICOPEPTIDE REPEAT PROTEIN, TPR
PTHR23083:SF23 [374-470]T 2.4e-07 PTHR23083:SF23 O-GLCNAC TRANSFERASE, P110 SUBUNIT-RELATED O-GLCNAC TRANSFERASE, P110 SUBUNIT-RELATED
PS51257 [1-21]T 6.000 PS51257 PROKAR_LIPOPROTEIN PROKAR_LIPOPROTEIN
signalp [1-23]? NA signalp signal-peptide signal-peptide
tmhmm [5-23]? NA tmhmm transmembrane_regions transmembrane_regions


COGS Summary:  COGS Search
BeTs to 9 clades of COG0457
COG name: TPR-repeat-containing proteins
Functional Class: R
The phylogenetic pattern of COG0457 is AMTKYQVCEB-HUJ--OLINX
Number of proteins in this genome belonging to this COG is 21
Blocks Summary:  Blocks Search
No significant hit to the Blocks database.

 ProDom Summary:  Protein Domain Search
Residues 107-353 are 26% similar to a (FIMBRILIN) protein domain (PD142733 which is seen in O07074_PORGI.


Paralogs:  Local Blast Search
Residues 56-368 are 25% similar to PG1893, a predicted immunoreactive 53 kD antigen PG123. Residues 107-353 are 26% similar to PG1864, a hypothetical protein.

Pfam Summary:  Pfam Search
No significant hits to the Pfam 11.0 database

 Structural Feature(s):
Feature Type  Start  Stop
gram negative signal  
1  
23
coil-coil  
67  
95
coil-coil  
113  
147
non-globular  
302  
384

Top PDB Hits:
No significant hits to the PDB database (E-value < E-10).

Gene Protein Sequence:
MLKKIFSVLLVCSAAVVISSCSGKLRPVTADLVKAEPQPLEVVGSKVPVT
VSIAFPAKWFNKKAELTVKPVLRYATGESWGPSFLFQGEKVLGNERVVSY
DNGGNQQLVFSFPYKPAMDKSELFLTFEAKVKGKKINLPDLKIADGVIST
EALASALNASAAIAPDAFQRIIKQAYDANIMFLIQQAQIRAQEINKGEVK
DWKDLVANAKDAPNQDVTVEVQAYASPDGGVELNEKLSEQREKNTTTALK
KQFQKSNIKDVEINAHYTAQDWEGFKQLVEKSDIQDKELVLRVLSMYPDP
EQREQEIKNISTVFRQLADDILPQLRRSRLIANVEIIGKSDDEIKRLAAQ
NPGRLTVEELLYSATLLESPAQKEDIYKVATQIYPDDYRAYNNIGMMRYR
SGDLEGARTWFQKAASVKPNAETDMNLGLLALNEGNVEQAKQYFGSAANV
PELGEALGLLYLQEGNYAQAVAAFGKTESNNAAVANILNRDYNRAQEILN
GIKNPDATTYYLMAVVAARTNNLDVVINSLRESISLDSSMMKKAATDLEF
AKYANDGGFKSLLRH

Gene Nucleotide Sequence:  Sequence Viewer
ATGCTTAAGAAAATCTTTTCTGTACTACTCGTTTGCTCGGCAGCGGTAGT
CATCTCTTCCTGCTCCGGCAAATTACGTCCTGTGACTGCCGATTTGGTAA
AGGCTGAGCCACAACCACTCGAAGTCGTGGGAAGCAAAGTGCCTGTGACC
GTGAGTATCGCTTTTCCTGCCAAATGGTTCAATAAGAAAGCCGAACTTAC
AGTGAAGCCTGTGCTGCGCTATGCTACAGGTGAATCATGGGGACCTTCAT
TCCTTTTTCAGGGAGAAAAAGTACTTGGCAATGAGCGTGTAGTCAGCTAT
GACAATGGTGGCAATCAGCAGCTCGTATTCTCTTTCCCTTATAAGCCGGC
CATGGACAAGAGTGAACTCTTCTTAACCTTCGAAGCCAAAGTAAAAGGGA
AGAAAATAAATCTTCCGGATCTCAAAATCGCTGATGGTGTAATCAGTACG
GAAGCCTTGGCTTCTGCTCTTAATGCATCGGCGGCAATCGCTCCGGATGC
ATTCCAGCGCATCATCAAGCAAGCCTATGATGCAAATATCATGTTCCTCA
TCCAACAGGCACAGATTCGTGCACAAGAAATCAACAAGGGTGAGGTGAAA
GACTGGAAAGACTTGGTGGCCAATGCCAAGGATGCTCCCAATCAGGATGT
AACGGTGGAGGTACAAGCCTACGCTTCTCCTGATGGCGGTGTGGAGCTGA
ACGAAAAGCTGTCCGAGCAGCGCGAGAAAAATACGACTACTGCTCTGAAG
AAACAATTCCAAAAGAGCAATATCAAGGATGTAGAGATCAATGCACACTA
TACGGCACAGGACTGGGAAGGCTTCAAGCAGCTTGTGGAGAAAAGCGATA
TTCAGGACAAGGAACTTGTTCTGCGTGTTCTCTCCATGTATCCGGATCCC
GAGCAGCGTGAGCAGGAGATCAAGAATATCTCTACCGTATTCAGACAGCT
GGCGGATGATATCCTGCCCCAATTGCGTCGTTCGCGCCTTATCGCCAATG
TCGAAATCATAGGTAAGAGCGATGACGAGATCAAACGTCTTGCAGCCCAG
AACCCCGGCCGGCTGACCGTGGAGGAGCTGCTCTATAGTGCTACTCTGCT
CGAATCTCCTGCTCAAAAGGAAGATATTTACAAGGTGGCTACTCAGATCT
ATCCGGATGACTATCGTGCTTATAACAATATCGGTATGATGCGTTATCGC
AGCGGTGATTTGGAGGGTGCTCGTACTTGGTTCCAAAAGGCTGCAAGCGT
GAAGCCCAATGCAGAAACGGATATGAACCTTGGACTATTGGCTCTTAACG
AGGGTAATGTAGAGCAGGCTAAGCAGTATTTCGGCTCGGCTGCCAATGTG
CCCGAATTGGGCGAAGCTCTTGGTTTGCTCTATCTGCAAGAGGGCAATTA
TGCCCAGGCTGTAGCGGCTTTCGGTAAGACCGAGAGCAACAATGCTGCCG
TGGCCAATATCCTCAATCGCGACTACAACCGAGCACAAGAGATCCTGAAT
GGGATAAAGAATCCCGATGCTACTACTTATTACCTCATGGCTGTTGTGGC
TGCACGTACGAACAACTTGGACGTTGTAATAAATTCGCTCCGTGAATCCA
TCAGTCTCGATAGCAGTATGATGAAGAAAGCCGCTACGGATCTGGAGTTC
GCCAAGTATGCAAACGACGGAGGTTTCAAGTCATTGCTCCGCCAC

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