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Porphyromonas gingivalis Search Results

Record: 1 of 1  
MiniMap IGR0809 IGR0811 IGR0805 IGR0806 IGR0810 IGR0807 IGR0808 PG0941.1 ISPg2, - PG0943 PG0949 PG0945 ctfA, - PG0948 pyrD, - PG0947 prc,tsp, - PG0942 pal, - PG0941 PG0941.1 ISPg2, - PG0943 PG0949 PG0945 ctfA, - PG0948 pyrD, - PG0947 prc,tsp, - PG0942 pal, - PG0941 PG0941.1 ISPg2, - PG0943 ctfA, - PG0948 pyrD, - PG0947 prc,tsp, - PG0942 pal, - PG0941 pyrD, - PG0946 pyrD, - PG0946 PG0945 PG0949


LANL Gene ID: PG0943

GenBank Locus Tag: PG1061

DNA Molecule Name:
1  

GenBank ID:
34540798

Gene Name:
ISPg2  

Definition:
ISPg2-related (PGIS2-related) transposase

Cellular Location:
Cytoplasm [Evidence]

Gene Start:
1129910

Gene Stop:
1128825

Gene Length:
1086

Molecular Weight*:
41415

pI*:
6.60

Net Charge*:
-2.70

EC:
 

Functional Class:
Transposon functions  

Gene Ontology:
Biological process
  GO:0006313    transposition, DNA-mediated

Molecular function
  GO:0003677    DNA binding
  GO:0004803    transposase activity


Pathway: pathway table

Primary Evidence:
Wang,C.Y., Bond,V.C. and Genco,C.A.
Identification of a second endogenous Porphyromonas gingivalis
insertion element. J. Bacteriol. 179 (11), 3808-3812 (1997)

Comment:
Other than the weak similarity to PG1795, PG0943 is only similar to ISPg2 defined elements.

Member of IS5 family of elements. PG0943 is a variant of full-length ISPg2 elements such as PG1522.

TIGR ID: PG1061

Human Oral Microbiome Database:
View in HOMD Genome Viewer

Blast Summary:  PSI-Blast Search
PG0943 is 36% similar to a previously sequenced protein (PGIS2 transposase) of P. gingivalis in GenBank AAC45368.

Numerous significant hits in gapped BLAST; e.g. residues 6-356 are 32% similar to emb|CAB82577.1| hypothetical protein of Klebsiella pneumoniae, residues 6-360 are 33% similar to gb|AAG54543.1|AE005200_5 Z0275 gene product of Escherichia coli O157:H7, residues 5-361 are 33% similar to gb|AAC82490.1| RfbQRSO22-4 of Vibrio cholerae.

Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|34540798|ref|NP_905277.1|  ISPg6, transposase [Porphyromo...   719   0.0  
 gi|126659959|ref|ZP_01731082.1|  transposase (IS4) [Cyanothe...   256   1e-66
 gi|87310869|ref|ZP_01092995.1|  putative transposase [Blasto...   228   4e-58
 gi|56475478|ref|YP_157067.1|  transposase (IS4) [Azoarcus sp...   219   2e-55
 gi|56475480|ref|YP_157069.1|  transposase (IS4) [Azoarcus sp...   219   3e-55
 gi|153207327|ref|ZP_01946064.1|  transposase, ISAs1 family [...   213   1e-53
 gi|91214690|ref|ZP_01251663.1|  putative H repeat-associated...   212   2e-53
 gi|29654002|ref|NP_819694.1|  transposase, ISAs1 family [Cox...   212   3e-53
 gi|95926640|ref|ZP_01309419.1|  hypothetical protein CburR_0...   212   3e-53
 gi|91215887|ref|ZP_01252856.1|  putative H repeat-associated...   212   4e-53


InterPro Summary:  InterProScan

InterPro
IPR002559
Domain
Transposase, IS4-like
PF01609 [102-332]T 1.3999989204989001E-11 PF01609 Transposase_11 Transposase_11


COGS Summary:  COGS Search
No hit to the COGs database.
Blocks Summary:  Blocks Search
***** PF01811 (Transposase) with a combined E-value of 2.1e-24.
    PF01811C    52-94
    PF01811E    124-171
    PF01811F    173-197
    PF01811D    99-126
    PF01811G    194-244


 ProDom Summary:  Protein Domain Search
Residues 122-251 are 42% similar to a (PROTEIN TRANSPOSASE REGION PUTATIVE) protein domain (PD004339 which is seen in P95492_PORGI.

Residues 248-312 are 50% similar to a (PROTEIN TRANSPOSASE PUTATIVE REGION) protein domain (PD004012 which is seen in Q44285_AERSA.


Paralogs:  Local Blast Search
PG0943 is a variant of full-length ISPg2 elements such as PG1522.
Residues 10-340 are 36% similar to PG1522, PG0775, PG1905, PG1185, PG0249, all predicted ISPg2 elements. Fragment 279-358 is 40% similar to PG1795.

Pfam Summary:  Pfam Search
Residues 102 to 332 (E-value = 7.5e-14) place PG0943 in the Transposase_11 family which is described as Transposase DDE domain (PF01609)

 Structural Feature(s):
Feature Type  Start  Stop
No predicted structural features.  
  

Top PDB Hits:
No significant hits to the PDB database (E-value < E-10).

Gene Protein Sequence:
MDVQVYFSKVEDPRVVGRCKHKLSDILVIALASYLCGGEDYESMHELCLE
RGASLRPPVELPNGCPSVDTFERVLQRIEPQSLYACLQVYGKELISDLEG
KHIAIDGKRLKGSKKKTGSTHILSAWVDEVSLSLAQETVAEKRNELQAIP
EVLDSLDLSGAVISINAMGTQTNIAEQIIQSEADYILSLKSNQKHLYEDV
QDYFTGQYRCHRYETLEKDHGRIEKRTYTTLLASEVFEEGEYSQWQGLRS
LIQVEREISSLEGETRIDRQYYISSLPPEDCQLIGQYIRGHWGIENRLHW
HLDVTFREDTCRARKDYSATNLNTLRKFALAIVSGHKDKLSLRKRLFKAA
LNIDYLKKLLKI

Gene Nucleotide Sequence:  Sequence Viewer
ATGGATGTACAAGTTTATTTTTCTAAGGTAGAAGATCCACGTGTAGTGGG
TCGTTGCAAGCATAAGTTAAGCGATATTCTAGTTATAGCACTGGCGAGTT
ATCTGTGTGGAGGCGAGGATTATGAGTCCATGCATGAACTTTGCTTAGAG
CGAGGAGCATCTCTTCGCCCACCGGTTGAGTTGCCGAATGGTTGTCCGAG
CGTAGACACCTTCGAAAGAGTGCTCCAACGTATTGAGCCTCAGTCTCTCT
ATGCTTGTCTTCAAGTTTATGGGAAAGAACTCATTAGCGACTTGGAAGGT
AAACATATCGCCATTGACGGCAAACGTCTGAAAGGATCGAAGAAGAAAAC
CGGCAGTACACATATTCTCTCAGCTTGGGTTGATGAAGTGAGTTTAAGCC
TTGCTCAAGAGACTGTTGCCGAGAAACGCAATGAGTTACAAGCCATTCCG
GAAGTTTTGGATAGCCTTGATTTGTCGGGAGCAGTCATCAGCATAAATGC
TATGGGGACTCAAACCAACATTGCCGAGCAGATCATCCAATCAGAAGCCG
ACTACATTCTAAGTCTCAAAAGCAATCAAAAACACTTGTATGAGGATGTT
CAGGATTACTTCACAGGACAATACAGGTGTCATCGTTATGAAACCTTGGA
GAAAGATCATGGTCGTATTGAGAAGAGGACTTATACCACATTACTAGCTT
CAGAGGTCTTTGAGGAGGGGGAATATAGTCAATGGCAAGGCTTGAGAAGT
TTAATTCAAGTGGAGCGTGAGATTAGTAGTTTAGAGGGAGAGACTCGCAT
AGATAGGCAGTATTATATCAGCAGTTTACCACCCGAGGATTGTCAGTTAA
TCGGACAATATATTCGAGGGCATTGGGGAATTGAGAATCGACTCCATTGG
CATTTGGATGTAACCTTTAGGGAGGATACTTGTCGAGCTCGTAAGGATTA
TTCAGCCACCAATCTAAACACGTTGAGAAAGTTTGCTTTAGCCATTGTAT
CCGGGCATAAAGACAAACTATCCTTACGGAAGAGGTTGTTCAAAGCTGCT
CTGAATATAGACTATCTCAAAAAGCTACTAAAGATT

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