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Porphyromonas gingivalis Search Results

Record: 1 of 1  
MiniMap IGR1015 IGR1019 IGR1021 IGR1020 IGR1014 IGR1018 IGR1016 IGR1017 IGR1022 PG1191 PG1186 PG1190 pyrE, - PG1188 ISPg1, - PG1184 PG1189 PG1192 PG1182 PG1183 PG1180 ISPg2, - PG1185 wcfI, - PG1181 PG1191 PG1186 PG1190 pyrE, - PG1188 ISPg1, - PG1184 PG1189 PG1192 PG1182 PG1183 PG1180 ISPg2, - PG1185 wcfI, - PG1181 Type: IS element, Name: ISPg1 fragment - 3 Type: IS element, Name: ISPg1 fragment - 3 Type: IS element, Name: ISPg2 - 4 PG1190 pyrE, - PG1188 ISPg1, - PG1184 PG1189 PG1187 PG1186 PG1191 PG1187 PG1192 PG1182 PG1183 PG1180 ISPg2, - PG1185 wcfI, - PG1181


LANL Gene ID: PG1185

GenBank Locus Tag: PG1350

DNA Molecule Name:
1  

Genomic Island ID:
24

GenBank ID:
34541036

 Gene Name:
ISPg2  

 Definition:
ISPg2 (PGIS2) transposase

 Cellular Location:
Cytoplasm [Evidence]

 Gene Start:
1431009

Gene Stop:
1432136

Gene Length:
1128

Molecular Weight*:
43313

pI*:
7.40

Net Charge*:
2.35

EC:
 

 Functional Class:
Other categories; Transposase  

 Gene Ontology:
Biological process
  GO:0006313    transposition, DNA-mediated

Molecular function
  GO:0003677    DNA binding
  GO:0004803    transposase activity


 Pathway: pathway table

 Primary Evidence:
Zhang Y, Wang T, Chen W, Yilmaz O, Park Y, Jung IY, Hackett M, Lamont RJ.
Differential protein expression by Porphyromonas gingivalis in response to secreted epithelial cell components.
Proteomics. 2005 Jan;5(1):198-211.
PMID: 15619293

 Comment:

Member of IS5 family of elements.

TIGR ID: PG1350

 Human Oral Microbiome Database:
View in HOMD Genome Viewer

 Blast Summary:  PSI-Blast Search
This sequence corresponds to 34398065 in Genbank.

Its nearest neighbor in the NR database is 56478910 from Azoarcus sp. EbN1.

 Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|34540119|ref|NP_904598.1|  ISPg2, transposase [Porphyromo...   717   0.0  
 gi|91214690|ref|ZP_01251663.1|  putative H repeat-associated...   222   3e-56
 gi|91215887|ref|ZP_01252856.1|  putative H repeat-associated...   221   5e-56
 gi|56475478|ref|YP_157067.1|  transposase (IS4) [Azoarcus sp...   187   1e-45
 gi|56475480|ref|YP_157069.1|  transposase (IS4) [Azoarcus sp...   187   1e-45
 gi|87307470|ref|ZP_01089614.1|  hypothetical protein DSM3645...   180   1e-43
 gi|87310239|ref|ZP_01092370.1|  putative H repeat-associated...   180   1e-43
 gi|87308374|ref|ZP_01090515.1|  hypothetical protein DSM3645...   179   2e-43
 gi|34540798|ref|NP_905277.1|  ISPg6, transposase [Porphyromo...   178   5e-43
 gi|119898341|ref|YP_933554.1|  putative H repeat-associated ...   176   2e-42


InterPro Summary:  InterProScan

InterPro
IPR002559
Domain
Transposase, IS4-like
PF01609 [110-344]T 5.69999708784002E-36 PF01609 Transposase_11 Transposase_11


COGS Summary:  COGS Search
No hit to the COGs database.
Blocks Summary:  Blocks Search
***** PF01811 (Transposase) with a combined E-value of 2e-24.
    PF01811A    0-35
    PF01811B    36-52
    PF01811E    134-181
    PF01811F    183-207


 ProDom Summary:  Protein Domain Search
Residues 132-264 are identical to a (PROTEIN TRANSPOSASE REGION PUTATIVE) protein domain (PD004339 which is seen in P95492_PORGI.

Residues 332-376 are identical to a (PUTATIVE TRANSPOSASE) protein domain (PD054580 which is seen in P95492_PORGI.

Residues 279-331 are identical to a (PROTEIN TRANSPOSASE PUTATIVE REGION) protein domain (PD004012 which is seen in P95492_PORGI.

Residues 1-131 are 83% similar to a (PUTATIVE TRANSPOSASE) protein domain (PD103322 which is seen in P95492_PORGI.


Paralogs:  Local Blast Search
PG1185 is identical to PG1522, PG1905, PG0775 and PG0249, all predicted ISPg2 elements. PG1185 is similar to PG0943 and weakly similar to PG1058, PG0889, PG1795 and PG1855.

Pfam Summary:  Pfam Search
Residues 110 to 344 (E-value = 5.8e-39) place PG1185 in the Transposase_11 family which is described as Transposase DDE domain (PF01609)

 Structural Feature(s):
Feature Type  Start  Stop
transmembrane  
22  
38
coil-coil  
43  
70
non-globular  
331  
376

Top PDB Hits:
No significant hits to the PDB database (E-value < E-10).

Gene Protein Sequence:
MYHSLFESLCMVPDPRIERKKIYPLDFLLLIVFLSTLSGNTSWYEIEDYA
EEYEEELKSLYEMLTGHQLMHTMPSHDTLNRSISLLDVEAFEGAYKRWIE
GFISATSGKHICIDGKTMRGVKKLSFDTQSHVVSAFSPQDMCSLAQLYID
RKTNEIPAIHQLLDLLDLNGAVVSIDAIGTQTAIAEQIIDKGGNYVLCVK
ANQSLSLQEIEAYFCPLFQKHILLDEQTELSHGRIETRRYESILNPLEIE
ANEVLTRWKGLRSIHKVVRKRRDKKSDKTSEEVAYYISSLTDVSSLKQAI
RGHWAIENKLHHCLDVYFGHDASHKRTRNVAQIMDIIQKINLLIIERLKT
NMKSSIPRIQKKLARMKPQQLITIQF

Gene Nucleotide Sequence:  Sequence Viewer
ATGTATCATTCTCTATTTGAAAGCCTCTGCATGGTTCCGGACCCACGGAT
AGAGCGTAAAAAAATTTATCCTCTTGATTTTTTACTGCTGATCGTTTTCC
TCTCTACACTCTCAGGCAATACCTCTTGGTATGAGATTGAAGATTATGCC
GAGGAATACGAAGAAGAATTGAAAAGTCTATACGAAATGCTTACCGGCCA
TCAGCTTATGCATACCATGCCTTCTCATGATACTCTCAACAGGAGCATCA
GTCTGTTGGATGTAGAAGCTTTTGAGGGGGCTTATAAGCGATGGATTGAA
GGCTTTATCTCGGCCACTTCGGGTAAACATATTTGCATTGATGGCAAGAC
GATGCGGGGAGTGAAGAAACTCTCTTTCGATACACAATCCCATGTCGTCT
CTGCCTTTTCACCACAAGATATGTGCAGTCTTGCCCAACTCTACATCGAC
CGAAAAACAAACGAAATACCGGCTATACATCAACTTCTTGATTTGCTTGA
CTTGAACGGGGCTGTTGTCTCCATTGATGCCATAGGTACACAAACTGCCA
TTGCCGAACAAATTATCGATAAGGGCGGAAACTATGTATTGTGTGTTAAA
GCGAATCAAAGTTTGAGTCTGCAAGAGATTGAAGCCTATTTCTGCCCTCT
TTTTCAGAAACATATCCTCCTTGACGAACAGACGGAACTATCTCACGGAC
GCATAGAAACACGTCGCTATGAAAGTATTCTCAATCCCTTGGAGATAGAA
GCCAACGAGGTATTAACTCGCTGGAAAGGCTTGAGGTCGATACACAAAGT
TGTACGCAAACGAAGGGATAAAAAGAGTGACAAAACGAGTGAAGAAGTGG
CCTACTACATTTCGTCATTAACAGATGTTTCTTCATTGAAACAAGCTATT
CGTGGGCATTGGGCGATAGAGAATAAGTTACACCACTGTTTGGATGTCTA
TTTCGGACACGATGCCTCGCACAAGAGAACGAGGAATGTGGCGCAGATTA
TGGATATCATTCAAAAGATTAATTTACTCATTATAGAGAGACTAAAAACG
AATATGAAGTCCTCAATCCCTCGCATCCAAAAGAAACTGGCTCGAATGAA
GCCACAACAACTAATCACAATACAATTT

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