LANL Gene ID: PG1231
GenBank Locus Tag: PG1400
DNA Molecule Name:
1
GenBank ID:
Gene Name:
ISPg1
Definition:
ISPg1 fragment
Cellular Location:
Cytoplasm, Extracellular [Evidence]
Gene Start:
1483000
Gene Stop:
1483233
Gene Length:
234
Molecular Weight*:
9005
pI*:
12.00
Net Charge*:
14.31
EC:
Functional Class:
Transposon functions
Gene Ontology:
Biological process
GO:0006313 transposition, DNA-mediated
Molecular function
GO:0003677 DNA binding
GO:0004803 transposase activity
Pathway: pathway table
Primary Evidence:
Hanley,S.A., Aduse-Opoku,J. and Curtis,M.A.
A 55-kilodalton immunodominant antigen of Porphyromonas gingivalis
W50 has arisen via horizontal gene transfer
Infect. Immun. 67 (3), 1157-1171 (1999)
Maley,J. and Roberts,I.S.
Characterisation of IS1126 from Porphyromonas gingivalis W83: a new member of the IS4 family of insertion sequence elements
Microbiol. Lett. 123 (1-2), 219-224 (1994)
Shibata,Y., Hayakawa,M., Takiguchi,H., Shiroza,T. and Abiko,Y.
Determination and characterization of the hemagglutinin-associated
short motifs found in Porphyromonas gingivalis multiple gene
products. J. Biol. Chem. 274 (8), 5012-5020 (1999)
Secondary Evidence:
Knight,A.I., Ni,H., Cartwright,K.A. and McFadden,J.J.
Identification and characterization of a novel insertion sequence, IS1106, downstream of the porA gene in B15 Neisseria meningitidis.
Mol. Microbiol. 6 (11), 1565-1573 (1992)
Comment:
Member of the IS5 family of elements.
TIGR ID: PG1400
Human Oral Microbiome Database:
View in HOMD Genome Viewer
Blast Summary: PSI-Blast Search
PG1231 is equivalent to the C-terminal regions of the previously sequenced AJ130872 and AB015879 in GenBANK. Residues 1-65 are 44% similar to residues 247-311 of the IS1106 sequence of N.meningitidis (AE002488).
Top Blast Hits: Updated monthly
Click here to view the entire PsiBlast results.
InterPro Summary: InterProScan
| InterPro IPR002559 Domain 
|
| |||||||
![[21-65]T 1.3e-07 PF01609 Transposase_11](http://www.ebi.ac.uk/InterProScan/images/H.gif){kind=small}
COGS Summary: COGS Search
No hit to the COGs database.
Blocks Summary: Blocks Search
No significant hit to the Blocks database.
ProDom Summary: Protein Domain Search
Residues 21-73 are 73% similar to a (TRANSPOSASE ORF7 INSERTION SEQUENCE) protein domain (PD187845 which is seen in Q9ZA61_PORGI.
Paralogs: Local Blast Search
PG1231 is similar to the C-terminal regions of PG0883, PG0730, PG1919, PG1798, PG1755, PG1662, PG1422, PG1267, PG1230, PG1184, PG1087, PG1062, PG1050, PG0918, PG0763, PG0756, PG0740, PG0686, PG0169, PG0044, PG0689, PG1099, PG0499, PG0420, PG1895, PG1665, PG1215, PG0839, PG1608, PG1159, all ISPg1-related elements.
Pfam Summary: Pfam Search
No significant hits to the Pfam 11.0 database
Structural Feature(s):
| Feature Type | Start | Stop |
| No predicted structural features. |
Top PDB Hits:
No significant hits to the PDB database (E-value < E-10).
Gene Protein Sequence:
MLKAHRGQALSESQKQLNRMISKTRCLIERTFGSIRRWFCGGRCRYRGLA
KTHTRNILEAMAYNLKRMPGLLVLQGAK
Gene Nucleotide Sequence: Sequence Viewer
ATGCTTAAGGCCCATCGAGGTCAAGCCCTCAGTGAAAGTCAGAAACAACT
CAATCGGATGATCAGTAAGACGCGCTGCTTGATAGAACGTACCTTCGGTA
GTATTCGACGATGGTTCTGTGGCGGACGATGTCGCTACCGAGGGTTAGCC
AAGACACATACCCGGAATATCCTTGAAGCTATGGCCTACAATCTCAAGCG
TATGCCGGGGCTTCTTGTGCTTCAAGGCGCAAAA