The Oralgen Team has assembled here the complete sequences of 9 plasmids found in five well-studied oral bacterial pathogens. The nine plasmids vary in size from a 3.6 Kb cryptic plasmid in Treponema denticola to the 580 Kb megaplasmid discovered in Prevotella intermedia. These plasmids' hosts occupy the same environment and it is anticipated that the plasmids may share other characteristics. This collection will facilitate comparison among themselves as well as comparison with the larger oral metagenome as it becomes available.
Although Helicobactor pylori is most well known as a cause of gastritis, gastric ulcers and carcinomas, it has also been located in dental plaque and implicated in recurrent aphthous ulcerations and for this reason 14 completely sequenced plasmids of H. pylori have also been included. (Kilmartin, C. 2002, Elsheikh and Mahfouz, 2005)
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