Streptococcus gordonii is a commensal bacteria that usually colonizes the human tooth surfaces and is an important member of community that forms dental plaque. This bacteria is known to be involved in development of dental caries and also considered as a potential causative agent of bacterial endocarditis. Streptococcus gordonii strain Challis is a laboratory strain used extensively due to its well-characterized transformation system. The primary publication describing the genome of Streptococcus gordonii is by Vickerman et al, 2007, "Genome-wide transcriptional changes in Streptococcus gordonii in response to competence signaling peptide". J Bacteriol. 189(21):7799-807.
The genome of Streptococcus gordonii was sequenced by The Institute for Genomic Research (TIGR) and work was funded by NIDCR. Genome size of Streptococcus gordonii is approximately 2.2 Mbp, has a G+C content of 42% and encodes 2051 proteins. Each gene record is identified by a gene id, for example: SGO_0001 to SGO_2051. Annotated genome of Streptococcus gordonii was kindly provided to us by Dr. Steven Gill from University at Buffalo (Previously from TIGR) and we have manually checked and curated the annotation. The Genome Annotation ToolKit (ATK) was used for determining final gene definitions.
Transporter analysis was automatically done using the TransAAP program to aid in identifying all potential transporters and manually compared with final annotation definitions to check accuracy of predictions.
Several references pertaining to Streptococcus gordonii Challis that might be of interest to researchers in oral biology are summarized here.
Please let us know if we have missed any relevent references.
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